Results 11 to 20 of about 150,516 (303)

The Infectious Diseases Consequences of Monkey Business [PDF]

Canadian Journal of Infectious Diseases and Medical Microbiology, 2008
Many microorganisms that affect humans have originated in animal species and have subsequently evolved to afflict humans (1). Many factors may contribute to the ability of infectious agents to cross the species barrier and include those related to the host, the pathogen and the host-pathogen environment.
JM Conly, BL Johnston
doaj   +3 more sources

Introducing human 3D skin models as a new serological diagnostic tool for severe autoimmune bullous diseases [PDF]

Frontiers in Immunology
Autoimmune bullous diseases (AIBDs) are acquired disorders characterized by autoantibodies targeting structural proteins of the skin and mucous membranes, resulting in blister formation.
Laura Huth, Laura Huth, Ruth Heise, Yvonne Marquardt, Manuela Jansen, David Kluwig, Morna Friederike Schmidt, Nicole Albuscheit, Verena von Felbert, CTC-A Translation Group, Stefan Jockenhoevel, Sebastian Huth, Amir S. Yazdi, Jens Malte Baron   +13 more
doaj   +2 more sources

Establishment of a novel cynomolgus monkey model of hyperuricemia [PDF]

Animal Models and Experimental Medicine
Background Chronic hyperuricemia is associated with complications such as gout and uric acid nephropathy, but uric acid also exhibits biological activities (e.g., antioxidant effects, potential neuroprotective properties against neurodegenerative ...
Ji‐Wei Wang, Le Zhang, Can Yang, Guan‐Cong Luo, Rui‐Chang Liu, Yan‐Jun Xu, Sheng Cheng, Wen‐Yu Jiang, Richard Ward, Yang Yang, Cheng Xiang, Shu An, Tian‐Rui Xu   +12 more
doaj   +2 more sources

Establishment of porcine and monkey colonic organoids for drug toxicity study

Cell Regeneration, 2021
Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li, Yalong Wang, Mengxian Zhang, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji, Ye-Guang Chen   +7 more
doaj   +1 more source

A draft map of rhesus monkey tissue proteome for biomedical research. [PDF]

PLoS ONE, 2015
Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases because of its manageable size and genetic and proteomic similarities with humans, proteomic research using rhesus monkeys still remains ...
Jin-Gyun Lee, Kimberly Q McKinney, Yong-Yook Lee, Hae-Na Chung, Antonis J Pavlopoulos, Kook Y Jung, Woong-Ki Kim, Marcelo J Kuroda, David K Han, Sunil Hwang   +9 more
doaj   +1 more source

Sequence Analysis of Macaca mulatta TRIM4 and Its Role in the Interferon Pathway

Frontiers in Veterinary Science, 2022
Monkey diseases are becoming increasingly severe, and some may be transmitted to humans through direct and indirect contact. Innate immunity is the first line of defense against foreign microorganisms.
Mengmeng Zhao, Huawei Li, Hang Zhang, Huiyang Sha, Liangzong Huang, Ruining Wang   +5 more
doaj   +1 more source

Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging

Frontiers in Cell and Developmental Biology, 2021
Vascular aging is a potent driver of cardiovascular and cerebrovascular diseases. Vascular aging features cellular and functional changes, while its molecular mechanisms and the cell heterogeneity are poorly understood.
Fei Ge, Qi Pan, Yue Qin, Mengping Jia, Chengchao Ruan, Xiangxiang Wei, Qing Jing, Xiuling Zhi, Xinhong Wang, Lindi Jiang, Elena Osto, Jieyu Guo, Dan Meng   +12 more
doaj   +1 more source

Heterogeneity of circulating CD4+CD8+ double-positive T cells characterized by scRNA-seq analysis and trajectory inference

Scientific Reports, 2022
The frequency of CD4+CD8+ double-positive (DP) T cells is highly associated with a variety of diseases. Recently, we used high-throughput single-cell RNA sequencing to show that circulating DP T cells in cynomolgus monkeys comprise nine heterogeneous ...
Sung Min Choi, Hi Jung Park, Eun A Choi, Kyeong Cheon Jung, Jae Il Lee   +4 more
doaj   +1 more source

The basic reproductive ratio of the 2022 outbreak of the monkey pox virus disease for the United Kingdom, Canada, Brazil, the United Arab Emirates, and Nigeria

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background A recent outbreak of the monkey pox virus disease (MPVD) started to spread over the world before the second half of the 2022 year. This outbreak of the monkey pox virus disease is known as the 2022 outbreak of the monkey pox virus disease. The
Marwan Al-Raeei
doaj   +1 more source

Seasonal and spatial dynamics of the primary vector of plasmodium knowlesi within a major transmission focus in Sabah, Malaysia [PDF]

, 2015
Background The simian malaria parasite Plasmodium knowlesi is emerging as a public health problem in Southeast Asia, particularly in Malaysian Borneo where it now accounts for the greatest burden of malaria cases and deaths.
Chua, Tock H., Drakeley, Chris, Ferguson, Heather M., Fornace, Kimberly, Khaw, Loke T., Leong, Cherng S., Vythilingam, Indra, Wan-Sulaiman, Wan-Yusoff, William, Timothy, Wong, Meng L.   +9 more
core   +8 more sources