Molecular Cloning of Monkey Histamine H4 Receptor [PDF]
Histamine H4 receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H4 receptor was identified.
Tamaki Oda +8 more
doaj +2 more sources
CT anatomy and normal radiography of the skull of the Rhesus monkey (Macaca mulatta) [PDF]
Background Considering the relationship between human morphology and physiology with the Rhesus monkey, this animal is the most prominent species of laboratory primate for human and animal health research.
Ali Reza Vajhi +5 more
doaj +2 more sources
Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. [PDF]
Groundbreaking studies showed that differentiated somatic cells of mouse and human origin could be reverted to a stable pluripotent state by the ectopic expression of only four proteins.
Katharina Debowski +8 more
doaj +3 more sources
Mass spectrometry-based identification and whole-genome characterisation of the first pteropine orthoreovirus isolated from monkey faeces in Thailand [PDF]
Background The pteropine orthoreovirus (PRV) was isolated from monkey (Macaca fascicularis) faecal samples collected from human-inhabited areas in Lopburi Province, Thailand. These samples were initially obtained to survey for the presence of hepatitis E
Nathamon Kosoltanapiwat +11 more
doaj +2 more sources
Monkey hybrid stem cells develop cellular features of Huntington's disease [PDF]
Background Pluripotent stem cells that are capable of differentiating into different cell types and develop robust hallmark cellular features are useful tools for clarifying the impact of developmental events on neurodegenerative diseases such as ...
Lorthongpanich Chanchao +9 more
doaj +2 more sources
Designing a solar powered automatic hand-dryer to combat the outbreak of ebola and monkey pox diseases in sub-Saharan Africa [PDF]
In recent times, the outbreak and the concomitant spread of Monkey pox and Ebola virus diseases across some countries of sub-Saharan Africa in electrifying waves was terrifying. The countries worst hit are Liberia, Sierra Leone, Ghana, and Nigeria.
U.K. Okpeki, A.O. Oyubu, A.U. Oyubu
doaj +3 more sources
Terahertz Spectroscopic Diagnosis of Myelin Deficit Brain in Mice and Rhesus Monkey with Chemometric Techniques [PDF]
While myelin deficit of the central nervous system leads to several severe diseases, the definitive diagnostic means are lacking. We proposed and performed terahertz time-domain spectroscopy (THz-TDS) combined with chemometric techniques to discriminate ...
Yi Zou +11 more
doaj +2 more sources
Establishment of a Rapid Lesion-Controllable Retinal Degeneration Monkey Model for Preclinical Stem Cell Therapy [PDF]
Background: Retinal degenerative disorders (RDs) are the main cause of blindness without curable treatment. Our previous studies have demonstrated that human-induced pluripotent stem cells can differentiate into retinal organoids with all subtypes of ...
Guanjie Gao +8 more
doaj +2 more sources
Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases [PDF]
Background Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site ...
Chu Chu +9 more
doaj +2 more sources
Molecular determinants of neuroprotection in blood-brain interfaces of the cynomolgus monkey [PDF]
The blood-brain barrier (BBB) formed by the cerebral microvessel endothelium and the blood-CSF barrier (BCSFB) formed by the choroid plexus epithelium impact the cerebral bioavailability of drugs and endogenous molecules that contribute to ...
Nathalie Strazielle +6 more
doaj +3 more sources

