Results 171 to 180 of about 401,656 (304)

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

From classification medicine to clinical medicine (the end of the XVIII century - 1870s). Communication 5. Reforms in therapy in 1840s-1860s

Терапевтический архив, 2012
Reforms of therapy in 1840-1860s are considered: development of the methods of objective assessment of efficacy of some methods of treatment, appearance of experimental pharmacology, introduction of anasthesia.
Andrey Mikhaylovich Stochik, Sergey Narkizovich Zatravkin, A M Stochik, S N Zatravkin   +3 more
doaj  

Chloroform

International Journal of Clinical Practice, 1955
openaire   +2 more sources

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

The purfication of chloroform vapors using a novel non-thermal plasma reactor (2015)

Salāmat-i kār-i Īrān, 2017
Background and aims: One of the innovative technologies for air pollution control is non-thermal plasma. The dielectric barrier discharge reactor is one of the reactors that applied in non thermal plasma technology for air polluation control.
hossein ebrahimi, Abdulrahman Bahrami, Mahmoud Nasrollahzadeh, Iraj Alimohammadi, Babak Jaleh, Kamaleddin Abedi, Farshid Ghorbani Shahna, Sayed Hosein Tabatabaei   +7 more
doaj  

Criteria document chloroform

, 2017
Dit rapport bevat een systematisch overzicht en een kritische evaluatie van de belangrijkste gegevens over de prioritaire stof chloroform.
van der Heijden CA, Knaap AGAC, de Jong P, Lanting RW, Huygen C, Heijna-Merkus E, Duiser JA, Speijers GJA, Janssen PJCM, Ros JPM, Gerlofsma A, Besemer AC, Mennes WC, Bergshoeff G, van der Most PJF, de Vrijer FL, Maas RJM, Huldy HJ   +17 more
core  

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

The effects of metal ion and ligand substitution on the spectroscopic properties of metal complexes.

, 1975
Includes bibliographical references.Metal-nitrogen stretching vibrations in Co(II), Ni(II), Cu(II) and Zn(II) chloride 4-methylaniline complexes are assigned by ¹⁵N-labelling in conjunction with a consideration of the relative crystal field ...
Johnson, Peter Robin
core  

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Preliminary Phytoconstituent Analysis and In Vitro Evaluation of Antibacterial and Antioxidant Activities of <i>Verbascum sinaiticum</i> Benth Leaf Extracts. [PDF]

J Trop Med
Wodajo AT, Mekonnen BA, Mekuria SL, Manahelohe GM.   +3 more
europepmc   +1 more source