Results 151 to 160 of about 426,716 (263)

Design, synthesis, and biological evaluation of naphthalimide derivatives as dual monoamine oxidase-B and amyloid-β aggregation inhibitors for Alzheimer's disease. [PDF]

RSC Adv
Praveen R, Gadaleta A, Spada G, Miniero DV, Reza A, Chaudhari TY, Rahman A, Catto M, Hoda N.   +8 more
europepmc   +1 more source

Genome‐Wide and Multi‐Omics Analysis Identified DNA‐Interacting Circular RNA circFOXK2 as MLL1 Regulator for Histone H3K4 Methylation in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Circular RNA circFOXK2 is frequently upregulated in pancreatic ductal adenocarcinoma to promote tumor heterogeneity, growth, and metastasis. Through circRNA‐DNA interaction at different genomic locations, circFOXK2 removes the PPIE inhibitory effects on MLL1 for gene‐activating H3K4 methylation of the oncogenes.
Chi Hin Wong, Jessica Jazmin Peña‐Paladines, Sum Yin Valerie Leung, Ka‐Fai To, Kenneth Siu Ho Chok, Yangchao Chen   +5 more
wiley   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Volatomic profiling of blood identifies environmental chemicals associated with metabolic dysfunction-associated steatotic liver disease in lean US adults. [PDF]

Proc (Bayl Univ Med Cent)
Njei B, Halwani KW, Gyabaah S, Boateng S, Nguefang GL, Al-Ajlouni YA, Kanmounye US.   +6 more
europepmc   +1 more source

Evaporation Kinetics Engineering Suppressed Bimolecular Recombination in All‐Polymer Solar Cells

Advanced Science, EarlyView.
In this study, phenanthrene (Ph), a volatile solid additive with a weak tendency toward self‐aggregation, is introduced as a donor‐selective morphology regulator in benchmark all‐PSC systems. The moderate evaporation kinetics of Ph enable cooperative crystallization of donors and acceptors, leading to an increased fractal dimension with reduced donor ...
Dinglong Feng, Le Mei, Chao Li, Yuang Fu, Heng Liu, Luhang Xu, Pok Fung Chan, Zhixiang Yang, Yiming Wang, Chun‐Jen Su, U‐Ser Jeng, Patrick Wai‐Keung Fong, Lijian Zuo, Gang Li, He Yan, Jiaying Wu, Xian‐Kai Chen, Xinhui Lu   +17 more
wiley   +1 more source

Secondary Metabolite Profiling, In Vitro Antimicrobial Activity Evaluation, and In Vivo Acute Toxicity Assessment of <i>Osyris quadripartita</i> and <i>Toddalia asiatica</i> Leaves and Stem Bark Extracts. [PDF]

J Trop Med
Tilahun E, Bussa NF, Belayneh A, Zelalem A, Kiros T.   +4 more
europepmc   +1 more source

Rapid Photogelation of Low‐Concentration Polymer Solutions via Photodimerization of o‐Ethylnitrobenzene

Advanced Science, EarlyView.
Upon UV irradiation, flexible and tough hydrogels are formed rapidly (>0.5 s) from dilute (>0.5 wt%) solutions of o‐ethylnitrobenzene–modified PVA. At ∼1.5 wt%, the hydrogels withstand up to 10 MPa compression, remain handleable even after 200‐fold swelling.
Masaaki Okihara, Ayaka Tomoda, Kana Morishita, Toshiyuki Takagi, Kimio Sumaru   +4 more
wiley   +1 more source

Optimization and Comparative Evaluation of DNA Extraction Protocols for Arbuscular Mycorrhizal Fungi in Coffee Roots. [PDF]

Methods Protoc
Gómez-Godínez LJ, Ortiz-Gasca A, Aguirre-Noyola JL, Ruvalcaba-Gómez JM, De Los Santos-Villalobos S, Arteaga-Garibay RI.   +5 more
europepmc   +1 more source

Terrestrial natural sources of trichloromethane (chloroform, CHCl3) - An overview

, 2002
The widespread use of volatile chlorinated compounds like chloroform, trichloroethene and tetrachloroethene in industrialized societies causes a large annual release of these compounds into the environment.
Gron, C,, Haselmann, KF,, Laturnus, Frank,, Borch, T,   +3 more
core  

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source