Results 51 to 60 of about 661,870 (283)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Radicals and Ions Formed in Plasma-Treated Organic Solvents: A Mechanistic Investigation to Rationalize the Enhancement of Electrospinnability of Polycaprolactone

Frontiers in Chemistry, 2019
This paper reports and discusses the beneficial effects on the quality of electrospun polycaprolactone nanofibers brought about by pretreatment of the solvent with non-thermal plasma.
Silvia Grande, Francesco Tampieri, Anton Nikiforov, Agata Giardina, Antonio Barbon, Pieter Cools, Rino Morent, Cristina Paradisi, Ester Marotta, Nathalie De Geyter   +9 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

CHLOROFORM ANÆSTHESIA.

The Lancet, 1904
Bibliography: p. [150]-155. ; Mode of access: Internet. ; UCSFB copy: Copies: 31272.
openaire   +1 more source

HPTLC assay of nicotine and cotinine in biological samples [PDF]

, 2018
This study presents the development of a simple high-performance thin layer chromatography (HPTLC) method for the determination of nicotine and its metabolite cotinine in human plasma and urine.
Baconi, Daniela Luiza, Balalau, Cristian, Ciobanu, Anne Marie, Constantin, Vlad D., Ples, Liana, Stan, Miriana, Vlasceanu, Ana Maria   +6 more
core   +1 more source

Heterogeneous Batch Distillation Processes: Real System Optimisation [PDF]

, 2008
In this paper, optimisation of batch distillation processes is considered. It deals with real systems with rigorous simulation of the processes through the resolution full MESH differential algebraic equations. Specific software architecture is developed,
B. Kotai, Bernot, Bernot, Betlem, Bonny, Bonny, Coward, Farhat, Farhat, Fernhloz, Fraga, Fraga, Frey, Furlonge, Gmehling, Hanke, Jang, Kao, Kim, Kiva, Lang, Lelkes, Modla, Mukherjee, Mutjaba, Noda, Novak, O. Baudouin, P. Floquet, P. Lang, Rodriguez-Donis, Rodriguez-Donis, Rodríguez-Donis, S. Massebeuf, S. Pommier, Skouras, Skouras, Sorensen, Spellucci, Spellucci, V. Gerbaud, Van Dongen   +41 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

DETERMINATION OF NECESSARY CONDITIONS FOR EFFICIENT PURIFICATION OF DRINKING WATER WITH HIGH CHLOROFORM CONTENT BY PLASMA TREATMENT IN AEROSOL

Геохімія техногенезу, 2021
Sustainable development of any country is possible only if the stable supply of its population with drinking water in accordance with their needs, quantity and regulatory quality.
Y. Zabulonov, D. Charny, L. Odukalec , D. Yaroshchuk , O. Puhach , O. Arkhypenko, N. Chernova   +6 more
doaj   +1 more source

Detonation hazards with ''safe'' industrial solvents [PDF]

, 1970
Sensitivities of various metal/halocarbon slurries to impact are given. Barium and lithium shavings show sensitivity with all of the halocarbons tested except methyl chloroform.
Fingerhood, C. R.
core   +1 more source