Results 61 to 70 of about 661,870 (283)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Bioactive Compounds From Torbangun [Plectranthus Amboinicus (Lour.) Spreng] Chloroform Fraction Induce Apoptosis in Breast Cancer (Mcf-7 Cells) in Vitro [PDF]

, 2017
Torbangun (Plectranthus amboinicus (Lour.) Spreng) is a medicinal plant that has been traditionally used in tropical countries to cure various illnesses.
Andarwulan, N. (Nuri), Giriwono, P. E. (Puspo), Pamungkas, J. (Joko), Yulianto, W. (Wahid)   +3 more
core  

Realization of generalized quantum searching using nuclear magnetic resonance

, 2001
According to the theoretical results, the quantum searching algorithm can be generalized by replacing the Walsh-Hadamard(W-H) transform by almost any quantum mechanical operation.
C. Zalka, D. G. Cory, E. Knill, I. L. Chuang, I. L. Chuang, Jingfu Zhang, L. K. Grover, L. K. Grover, L. K. Grover, L. K. Grover, Lu Shan, M. Boyer, Zhiheng Lu, Zhiwei Deng   +13 more
core   +1 more source

Influence of solvent choice on the optimisation of a reaction–separation operation : application to a Beckmann rearrangement reaction [PDF]

, 2004
In pharmaceutical syntheses, the solvent choice generally represents a complex design step. Traditionally, this choice is operated according to criteria connected with the reaction step and without any consideration on the following separation steps. The
Cabassud, Michel, Cezerac, Jérome, Cognet, Patrick, Elgue, Sébastien, Le Lann, Jean-Marc, Prat, Laurent E.   +5 more
core   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Kinetics of the photolysis of benzenetricarbonylchromium(0) in chloroform [PDF]

, 2000
In contrast to the photolysis of Cr(CO)3(C6H6) in nonhalogenated solvents, in which the products are CrL(CO)2(C6H6) in the presence of a donor L, or Cr(CO)6 and C6H6 if no donor is present, the photo-reaction in chloroform yields CrCl3.
Federici, Leslianna, Hoggard, Patrick E.
core   +1 more source

Formation of porous membranes for drug delivery systems [PDF]

, 1993
Highly crystalline porous hollow poly (-lactide) (PLLA) fibres suitable for the delivery of various drugs were obtained using a dry-wet spinning process.
Dijkstra, P.J., Eenink, M.J.D., Esselbrugge, H., Loman-Peters, A.M.P., Sam, A.P., Schakenraad, J.M., Witte, P. van de   +6 more
core   +3 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Dual‐Mode Film Based on Highly Scattering Nanofibers and Upcycled Chips‐Bags for Year‐Round Thermal Management

Advanced Functional Materials, EarlyView.
Intelligent radiative cooling devices, adaptable to various weather conditions, have the potential for year‐round energy savings. This study introduces a sustainable dual‐mode film made from polycaprolactone nanofibers and upcycled chip bags for effective thermal management.
Qimeng Song, Stefan Rettinger, Chengzhang Xu, Ulrich Mansfeld, Markus Retsch   +4 more
wiley   +1 more source