Results 121 to 130 of about 107,140 (318)

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

open access: yesInternational Journal of Antimicrobial Agents, 2020
C. Devaux   +3 more
semanticscholar   +1 more source

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

open access: yesAging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox   +13 more
wiley   +1 more source

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

open access: yesNature, 2020
M. Hoffmann   +9 more
semanticscholar   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

CAUTION WITH CHLOROQUINE: A CASE OF CHLOROQUINE CARDIOTOXICITY

open access: yesJournal of the American College of Cardiology, 2023
Pelter, Megan, Heywood, J. Thomas
openaire   +1 more source

Chloroquine and hydroxychloroquine as available weapons to fight COVID-19

open access: yesInternational Journal of Antimicrobial Agents, 2020
P. Colson   +4 more
semanticscholar   +1 more source

Management Strategies for Generalised Granuloma Annulare: A Systematic Review of Current and Emerging Therapies

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Generalised Granuloma Annulare (GGA) is a chronic inflammatory skin disorder with no standard treatment. Since the last review in 2013, new treatments and varied responses have highlighted the need for an updated synthesis to guide clinical decisions.
Luca Bettolini   +11 more
wiley   +1 more source

Chloroquine-resistant malaria in West Malaysia. [PDF]

open access: bronze, 1968
T.P.H. McKelvey   +4 more
openalex   +1 more source

Juvenile idiopathic arthritis during 20 years in Sweden: Characteristics of children, therapy interventions, occurrence of uveitis and ocular complications

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess and compare the characteristics, therapy interventions, occurrence of uveitis and ocular complications in children with juvenile idiopathic arthritis (JIA) screened and examined for uveitis in Gothenburg, Sweden, over 20 years.
Pia Lundgren   +7 more
wiley   +1 more source

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