Results 271 to 280 of about 178,293 (355)

Reaction of N‐Ferrocenylcarbamates with Nitric Oxide: An Application for Detection of Inflammatory Sites In Vivo

ChemMedChem, Volume 20, Issue 19, October 6, 2025.
Nitric oxide induces decomposition of electron‐deficient aminoferrocene drugs 4 with formation of oxime 7, which is derived from the upper cyclopentadienyl ligand. Drugs 4 are not responsive to hydrogen peroxide. Based on the latter reaction, the fluorogenic probes are developed for detecting NO in cells and inflammation in vivo.
Roman Selin, Hülya Gizem Özkan, Galyna Bila, Rostyslav Bilyy, Andriy Mokhir   +4 more
wiley   +1 more source

Translation of a Human-Based Malaria-on-a-Chip Phenotypic Disease Model for In Vivo Applications. [PDF]

Adv Sci (Weinh)
Rupar MJ, Hanson HM, Botlick BL, Sriram N, Rogers S, Zuniga J, Liu Z, Trimmer SJ, Ciurca JM, Long CJ, McAleer CW, Schmidt S, Favuzza P, Lowe P, Gobeau N, Hickman JJ.   +15 more
europepmc   +1 more source

TOXICOLOGICAL STUDIES ON THE CHLOROQUINE-MELANIN AFFINITY IN VIVO AND IN VITRO IN RELATION TO THE CHLOROQUINE RETINOPATHY

, 1976
Yutaka Kasuya, Hiroshi Miyata, Minoru Watanabe   +2 more
openalex   +2 more sources

C1′‐Branched Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium Falciparum 6‐Oxopurine Phosphoribosyltransferase

ChemMedChem, Volume 20, Issue 19, October 6, 2025.
Novel C1'‐branched acyclic nucleoside phosphonates were synthesized. The compounds are inhibitors of Plasmodium falciparum and human 6‐oxopurine phosphoribosyltransferases with Ki values as low as 0.4 µM and 0.7 µM, respectively. A phosphonodiamidate prodrug exhibited IC50 = 4.3 µM against a drug‐sensitive strain of P.
Jan Frydrych, Dianne T. Keough, Haojun Xia, Lenka Poštová Slavětínská, Martin Dračínský, Michal Česnek, Jye Travis, Marina Chavchich, Michael Edstein, Dana Hocková, Luke W. Guddat, Zlatko Janeba   +11 more
wiley   +1 more source

Eyelid nodule with persistent growth. [PDF]

JAAD Case Rep
Hoellwerth M, Brandlmaier M, Selhofer S, Laimer M, Koelblinger P.   +4 more
europepmc   +1 more source

Inoculum effect with chloroquine and Plasmodium falciparum [PDF]

, 1987
Ilya Y. Gluzman, Paul H. Schlesinger, Donald J. Krogstad   +2 more
openalex   +1 more source

Plasmodium falciparum isolates: ex vivo drug response. [PDF]

J Antimicrob Chemother
Adika E, Saiid S, Amoako EK, Sakyi ME, Osumanu A, Morang'a C, Dosoo D, Chirawurah JD, Awandare GA, Amambua-Ngwa A, Aniweh Y, Amenga-Etego LN.   +11 more
europepmc   +1 more source

Effect of Ammonium Chloride on the Excretion of Chloroquine in Rabbit Urine

, 1977
Kimie Murayama, Kyoko Kobayashi, MINORU FUTEMMA, Akira Nakajima   +3 more
openalex   +2 more sources

Report on chloroquine and dapsone in the treatment of rheumatoid arthritis: a 6-month comparative study. [PDF]

, 1984
P D Fowler, M F Shadforth, P. R. Crook, A. LAWTON   +3 more
openalex   +1 more source

Emergence of chloroquine-sensitive <i>Plasmodium falciparum</i> and rising resistance to first-line artemisinin partner drugs in Malawi. [PDF]

Emerg Microbes Infect
Mazigo E, Jun H, Lee WJ, Louis JM, Syahada JH, Fitriana F, Muh F, Ahmed MA, Lu F, Han JH, Kwon TH, Lee SJ, Na S, Chun W, Park WS, Han ET, Kidima W, Han JH.   +17 more
europepmc   +1 more source