Results 151 to 160 of about 4,532 (203)
Risk of Hyponatremia with Diuretics: Chlorthalidone versus Hydrochlorothiazide
American Journal of Medicine, 2014 BACKGROUND: Chlorthalidone and hydrochlorothiazide are often considered as interchangeable. However, greater (nighttime) blood pressure reduction, and alleged pleiotropic effects have renewed the interest in chlorthalidone.
Bruno Stricker +2 more
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Automated Analysis of Chlorthalidone
Journal of Pharmaceutical Sciences, 1979Chlorthalidone inhibition of the enzymatic hydrolysis rate of p-nitrophenyl acetate by bovine erythrocyte carbonic anhydrase was used as a basis for chlorthalidone determination in plasma and urine. For urinary samples, a completely automated, continuous flow system was developed to extract the samples and perform the enzymatic reaction.
M M, Johnston, M, Rosenberg, B, Kamath
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Chlorthalidone – a renaissance in use?
Expert Opinion on Pharmacotherapy, 2009Diuretic therapy remains a mainstay of hypertension treatment, either given as monotherapy or used in combination with other antihypertensive compounds. Several issues have complicated the issue of diuretic use with that of class effect being the one that has proven most difficult.
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Treatment of Hypoparathyroid Patients with Chlorthalidone
New England Journal of Medicine, 1978In an effort to maintain normal serum calcium levels without inducing hypercalciuria, we treated seven hypoparathyroid patients for up to 25 months with chlorthalidone, a thiazide-like sulfonamide diuretic, plus a salt-restricted diet, without added vitamin D.
R H, Porter +5 more
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Optimization of a Tablet Containing Chlorthalidone
Drug Development and Industrial Pharmacy, 1999In pharmaceutical technological research, optimization studies generally deal with the search for the formulation that is as effective and as functional as possible. The effect of a formulation parameter (the amount of lactose in the composition of the tablets) and of a technological parameter (compression pressure) on four physical characteristics ...
G C, Ceschel, P, Maffei, R, Badiello
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Biliary excretion of chlorthalidone in humans
Biopharmaceutics & Drug Disposition, 1980AbstractA single oral dose of the diuretic chlorthalidone (100 or 200 mg) was given to six cholecystectomized patients with T‐tube drainage of the common bile duct, and the 24 h bile and urine were collected during 3–7 days. Urinary recovery of chlorthalidone was 23–27 per cent of the dose, which is in the range of that in healthy volunteers ...
H L, Fleuren +2 more
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