Results 191 to 200 of about 659,838 (261)

DTT-Induced Transcriptome Profiling Reveals Divergent ER Proteostasis and Stress-Adaptation Programs in CHO-S/HB8 and CHO-4BGD/DUL Producer Clones. [PDF]

Int J Mol Sci
Orlova NA, Potapova NA, Shaifutdinov RR, Vorobiev II.   +3 more
europepmc   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Ceratohyoidectomy for Management of Unilateral and Bilateral Temporohyoid Osteoarthropathy: Long-Term Outcome in 33 Equids. [PDF]

Animals (Basel)
McCrary HS, Stewart HL, Davis JG, Garcia-Lopez JM, Bubeck KA.   +4 more
europepmc   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source

Biomimetic spatial compartmentalization directs C1 intermediate evolution for highly selective CO₂ photomethanation. [PDF]

Chem Sci
Li Y, Zhao X, Chen Y, Chen Y, Zheng J, Liu Z.   +5 more
europepmc   +1 more source

Co‐Ligand‐Induced Electronic Modulation Controls Substrate Adsorption and Selectivity in Biomass Electrooxidation

Advanced Science, EarlyView.
A molecular design strategy is reported that introduces distinct anionic co‐ligands into Cu‐based catalysts to modulate the electronic density of the metal center and, consequently, its interaction with both OHads and HMF. The work establishes co‐ligand engineering as an effective strategy for precise interfacial adsorption control in electrocatalysis,
Chen Gao, Bin Han, Shuai Chen, Shuai Yan, Ralf Weisbarth, Jorg Daniels, Nikolay Kornienko   +6 more
wiley   +1 more source

Nutrition as a neglected domain of post-intensive care syndrome in children. [PDF]

Acute Crit Care
Choi I, Kim WK, Cho HJ.
europepmc   +1 more source

Regarding 'efficacy analysis of combined nerve combing and decompression for occipital neuralgia based on the classification of neurovascular relationships'. [PDF]

Ann Med
Cho CB.
europepmc   +1 more source

Hitting the Wall in Marathon Running: An Integrative Psychophysiological and Durability-Based Review. [PDF]

J Funct Morphol Kinesiol
Grivas GV, Alkasasbeh WJ, Amawi AT.
europepmc   +1 more source

A Novel Anti-Cadherin-17 Monoclonal Antibody, Ca₁₇Mab-5, for Multiple Applications. [PDF]

Antibodies (Basel)
Ito R, Suzuki H, Ishikawa K, Yagi K, Ohkoshi A, Katori Y, Kaneko MK, Kato Y.   +7 more
europepmc   +1 more source