Results 191 to 200 of about 228,451 (311)

Scaled up fed-batch production of recombinant alpha-1-antitrypsin by CHO cells in single-use surface aerated orbital shaken bioreactor. [PDF]

Sci Rep
Tang WQ, Jiang CQZ, Zheng ZY, Lau A, Bi X, Zhang W, Ng SK.   +6 more
europepmc   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

MemorySeq identifies heritable epigenetic phenotypes that initiate cell culture stress tolerance in CHO cells. [PDF]

iScience
Grissom S, Dixon Z, Singh A, Blenner M.
europepmc   +1 more source

Engineered CHO cells as a novel AAV production platform for gene therapy delivery. [PDF]

Sci Rep, 2023
Nagy A, Chakrabarti L, Kurasawa J, Mulagapati SHR, Devine P, Therres J, Chen Z, Schmelzer AE.   +7 more
europepmc   +1 more source

Sliding Ferroelectricity Driven Spin‐Layertronics in Altermagnetic Multilayers

Advanced Science, EarlyView.
Integrating sliding ferroelectricity with altermagnetism enables nonvolatile electrical control of spin and layer degrees of freedom. In bilayer CuF2, interlayer translation reverses layer‐locked spin‐split bands, establishing a multifunctional “spin‐layertronic” platform.
Rui Peng, Guangxu Su, Yangyang Fan, Jiaan Li, Fanxin Liu, Yee Sin Ang   +5 more
wiley   +1 more source

P-glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells. [PDF]

FEBS Lett
Busche R, Riordan JR, Tümmler B.
europepmc   +1 more source

Confinement‐Driven CO Spillover in CuAg@MSN Tandem Catalysts Boosts C2 Selectivity Toward Electrocatalytic CO2 Reduction

Advanced Science, EarlyView.
The CuAg@MSN catalyst developed in this study promotes C─C coupling by regulating the coverage of *CO intermediates through spatial confinement effects, significantly enhancing the selectivity of CO2 electroreduction for C2 product formation. ABSTRACT Tandem catalysts represent a promising paradigm for synergistic electrochemical CO2 reduction (CO2RR ...
Jiaying Zhang, Junjie Huang, Siying Zhang, Yanjia Cui, Chao Kong, Zijian Peng, Huihui Jiang, Sirui Deng, Zhuoyao Chen, Caili Yang, Ketong He, Zhen Li, Yibing Song, Gongwei Wang, Lin Zhuang   +14 more
wiley   +1 more source

SETDB1 knockdown boosts recombinant protein in CHO cells via epigenetic transcriptional silencing. [PDF]

AMB Express
Lu JT, Zhang M, Gao YP, Yang LL, Cui ZM, Han MM, Zhang X, Xu HY, Wang XY, Qiu LL, Hua ZC, Wang TY, Jia YL.   +12 more
europepmc   +1 more source

Electrocatalytic Coupling Conversion of Methane by Dual‐Site Control in Nickel Oxyhydroxide

Advanced Science, EarlyView.
Electrocatalytic coupling conversion of methane (CH4) is accomplished on the nickel oxyhydroxide (NiOOH), wherein the Ni─O dual‐site is triggered via the proper electronic interaction, synergistically promoting the C─H activation and C─C formation, enabling a selective and efficient C2 product generation route under ambient conditions. ABSTRACT Methane
Kailong Lu, Yangshen Chen, Junhao Wang, Yi Zhang, Sunyang He, Huimin Xu, Hui Liu, Jiao Deng   +7 more
wiley   +1 more source

Flux Sampling Suggests Metabolic Signatures of High Antibody-Producing CHO Cells. [PDF]

Biotechnol Bioeng
Meeson KE, Watson J, Rosser S, Hawke E, Pitt A, Moses T, Pybus L, Rattray M, Dickson AJ, Schwartz JM.   +9 more
europepmc   +1 more source