Results 171 to 180 of about 4,711,608 (247)

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Defect‐Engineered LiYO2 Interlayers Enabling Fast Interfacial Li+ Transport in All‐Solid‐State Batteries

Advanced Science, EarlyView.
Defect‐engineered LiYO2 interlayers are designed through aliovalent Zn2+ and Zr4+ substitution to regulate Li+ point‐defect chemistry in Ni‐rich cathodes. Compared with Li‐excess‐type LYZnO, Li‐vacancy‐type LYZrO enables faster Li+ transport, suppresses Li6PS5Cl decomposition, lowers interfacial resistance, and mitigates polarization growth, thereby ...
Sodam Kim, Yun Seong Byeon, Jaewoo Jung, Mingyu Cho, Hyunmin Lee, Jung Ho Kim, Min‐Sik Park   +6 more
wiley   +1 more source

Granzyme B PET Imaging Reveals Lgmn+ Macrophage‐Mediated Immune Evasion and Guides Immunotherapy in EGFR‐TKI‐Resistant NSCLC

Advanced Science, EarlyView.
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang, Wenqin Luo, Qiufang Liu, Wenxuan Tang, Bin Zhu, Jiwei Chen, Qian Zhou, Shuang Tang, Xiaoping Xu, Shaoli Song   +9 more
wiley   +1 more source

Emerging Memory and Device Technologies for Hardware‐Accelerated Model Training and Inference

Advanced Electronic Materials, EarlyView.
This review investigates the suitability of various emerging memory technologies as compute‐in‐memory hardware for artificial intelligence (AI) applications. Distinct requirements for training‐ and inference‐centric computing are discussed, spanning device physics, materials, and system integration.
Yoonho Cho, Dae‐won Kim, Yujin Kim, Jung‐Heum Na, Yuwon Jeong, Dong‐Yeop Lee, Shinhyun Choi   +6 more
wiley   +1 more source

Bridging Performance and Fate: A Framework for Sustainable, Composite‐Based Flexible Electronic Systems

Advanced Electronic Materials, EarlyView.
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley   +1 more source

Multiscale Carbon‐Integrated Silicon Anode for Stable Cycling Under Practical Lithium‐Ion Battery Conditions

Advanced Energy Materials, EarlyView.
To overcome silicon anode instability, a hierarchical silicon/carbon composite fabricated from industrial waste via a scalable milling process is demonstrated. In‐depth post‐mortem analysis reveals how functional carbons—a CNT network and graphene shell—synergistically suppress degradation. This robust design delivers outstanding stability in practical
Young‐Ro Lee, Seong Chul Hong, Kyoungoh Kim, Jooha Park, Jihyeon Kim, Byungwook Kang, Youngsu Kim, Chaelin Lee, Soogyeong Son, Byungmo Cho, Junhyung Kim, Sang‐Gil Woo, Gwan‐Hyoung Lee, Kisuk Kang   +13 more
wiley   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Machine Learning Interatomic Potentials for Energy Materials: Architectures, Training Strategies, and Applications

Advanced Energy Materials, EarlyView.
Machine learning interatomic potentials bridge quantum accuracy and computational efficiency for materials discovery. Architectures from Gaussian process regression to equivariant graph neural networks, training strategies including active learning and foundation models, and applications in solid‐state electrolytes, batteries, electrocatalysts ...
In Kee Park, Saeed Pourasad, Jinhong Mun, Arunkumar Chitteth Rajan, Tae Hyeon Park, Anand Rohit, Mohammad Zafari, Tan‐Lien Pham, Eunjae Jung, Bonseung Koo, Miran Ha, Gi Beom Sim, Hyun Gyu Park, Won Woong Choi, Kwanghyeon Jo, Soohaeng Yoo Willow, David ChangMo Yang, Chang Woo Myung, Geunsik Lee, Kwang S. Kim   +19 more
wiley   +1 more source

Ultrathin Aluminum–Air Batteries via Hygroscopic Electrolytes for Continuous Operation of Imperceptible On‐Skin Electronics

Advanced Energy Materials, EarlyView.
This study presents ultrathin, high‐capacity aluminum‐air batteries (AABs) for self‐sustaining, skin‐conformal electronics. By utilizing ambient moisture and oxygen alongside a LiCl‐based hygroscopic hydrogel electrolyte, the design significantly reduces battery thickness while preventing dehydration and Al self‐corrosion.
Jaeil Park, Inho Lee, Namhee Kim, Wonseok Shin, Joo Sung Kim, Daegun Kim, Giwon Lee, Jinhan Cho, Hoon‐Hee Ryu, Myung‐Han Yoon, Seung Joon Yoo, Woo‐Jin Song, Sungjun Park   +12 more
wiley   +1 more source