Results 111 to 120 of about 3,012,805 (315)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

NARAL pamphlet "The Truth About Crisis Pregnancy Centers: Fact v. Fiction"

open access: yes, 2011
This pamphlet explains the danger of crisis pregnancy centers (CPCs) and defines fact and fiction about these ...
NARAL Pro-Choice America
core  

Patient preferences for long-acting antiretroviral treatment among people with HIV in Kenya: a discrete choice experiment

open access: yesBMC Infectious Diseases
Background For people with HIV (PWH), long-acting antiretroviral therapies (LA-ART) are promising treatment alternatives to daily oral regimens, with potential to improve adherence and achieve viral suppression.
Jacinda Tran   +10 more
doaj   +1 more source

On the Non-Obviousness of Our Readiness for the Choice and Mastering of Our Nature [PDF]

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2016
The paper discusses the problem of how humans master their nature, as well as their willingness to make the right life choice. The object of this research is the human nature, contradictory and striving for self-identity, while the subject is the non ...
Z.Z. Ibragimova
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

How to do a business plan : an in-depth guide using case studies

open access: yes, 1997
Physical Description: 1 videocassette (30 min.): sd., col.; 7 1/2 in..Every business needs a business plan. But how exactly do you write one? The video highlights the key issues people going into business need to consider: aims and objectives; marketing ...
TV Choice
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

NARAL Stand With Women Event Flyer

open access: yes, 2017
Flyer promoting attendance on Capitol steps in Olympia for National Women's ...
NARAL Pro-Choice Washington
core  

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