Results 121 to 130 of about 3,012,805 (315)

Institutionalizing uncertainty: the choice of electoral formulas

, 2009
Electoral formulas, Minimax choice, Uncertainty, Proportional representation,
Penadés De La Cruz, Alberto (author), Alberto Penadés, Fernández de Córdoba, Gonzalo, (author), Gonzalo Córdoba   +3 more
core   +1 more source

Willingness to pay for HIV pre- and post-exposure prophylaxis services delivered via an online pharmacy in Kenya

BMC Health Services Research
Background HIV pre- and post-exposure prophylaxis (PrEP/PEP) provision via online pharmacies could expand reach of HIV prevention in Eastern and Southern Africa, but designing sustainable delivery models will require assessing the amount potential users ...
Michalina A. Montaño, Yilin Chen, Enrique M. Saldarriaga, Nicholas Thuo, Catherine Kiptinness, Andy Stergachis, Melissa L. Mugambi, Kenneth Ngure, Katrina F. Ortblad, Monisha Sharma   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Freedom of choice and expected compromise

, 2010
This article develops a new measure of freedom of choice based on the proposal that a set offers more freedom of choice than another if, and only if, the expected degree of dissimilarity between a random alternative from the set of possible alternatives ...
Gustafsson, Johan E.,
core   +1 more source

Cost-effectiveness of primary care-based risk assessment and hereditary cancer genetic testing

BMC Primary Care
Background Guidelines recommend identifying individuals with a family or personal history of cancer, offering genetic testing, with the goal of managing disease risk.
Beth Devine, Sanne E. Aalbers, HuiHsuan Chan, Shangqing Jiang, Emerson J. Dusic, Sarah Knerr, Heather M. Harris, Catharine Wang, Barbara M. Norquist, Laurie A. Riemann, Jeannine M. Brant, Brian H. Shirts, Elizabeth M. Swisher   +12 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Marketing a service : three case studies

, 2000
This video looks at the experience of three well-known organisations marketing very different types of ...
TV Choice
core  

Neuromodulation of risk and reward processing during decision making in individuals with general anxiety disorder (GAD)

Scientific Reports
Individuals with general anxiety disorder (GAD) have an impaired future-oriented processing and altered reward perception, which might involve the ventromedial prefrontal cortex (vmPFC) and dorsolateral prefrontal cortex (dlPFC).
Vahid Nejati, Jamal Amani Rad, Amir Hosein Hadian Rasanan   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source