Results 141 to 150 of about 9,183,099 (304)

The Irony of Choice

, 2013
We are having the inevitable late night conversation. You talk about your eventual wedding, your marriage to the person you love, the timeline you’ve created for yourself, and your plans for what our future children will do together. I clarify that I don’
Nguyen, Cam T.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Triple-System Theory of Individual Decision-Making Based on the Concept of Flux

AlterEconomics
Although the topic of human decision-making is as vast as it is old, there is still no widely recognized computational model in both economic theory and interdisciplinary studies.
Victor A. ISTRATOV
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The concise argument – choice, choices and the choice agenda [PDF]

Journal of Medical Ethics, 2021
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Editors choice [PDF]

South African Medical Journal, 2010
openaire   +12 more sources

METODOLOGIA PARA AÇÕES COMUNITÁRIAS SUSTENTÁVEIS – PRÁTICAS DE INTEGRAÇÃO DO MODELO DAS CINCO HÉLICES EM UMA HORTA COMUNITÁRIA BRASILEIRA

Mix Sustentável
Este artigo apresenta o desenvolvimento de uma metodologia aplicável a ações comunitárias, desenvolvida a partir de fundamentos da pesquisa-ação participativa e dos valores do Design Sistêmico, Agroecologia, Soberania Alimentar e Economia Solidária, que
Rosângela Míriam Lemos Oliveira Mendonça, Samantha de Oliveira Nery , Ediméia Maria Ribeiro de Mello   +2 more
doaj  

Domain-specific effects of hunger on attention and choice. [PDF]

Sci Rep
March J, Ting CC, Park SQ, Gluth S.
europepmc   +1 more source