Results 121 to 130 of about 2,199,001 (304)

Selecting random parameters in discrete choice experiment for environmental valuation: A simulation experiment [PDF]

open access: yes
This paper examines the various tests commonly used to select random parameters in choice modelling. The most common procedures for selecting random parameters are: the Lagrange Multiplier test as proposed by McFadden and Train (2000), the t-statistic of
Abdullah, Sabah   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Consumer Choice of Modularized Products: A Conjoint Choice Experiment Approach [PDF]

open access: yes
Recent increases in flexibility and automation in the production of goods and services allow a growing number of suppliers to offer their products in flexible sets of modules from which consumers can create their own individualized packages.
Borgers, A.W.J.   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Consumer Preferences and Determinants of Transportation Mode Choice Behaviors in the Era of Autonomous Vehicles

open access: yesTransactions on Transport Sciences
The supply-side advancement in the transportation modes may bring a new mobility paradigm in the proximate future because consumers in the era of autonomous vehicles (AVs) would be able to choose from a variety of modes of transportation that would be ...
Sangwan Lee, Liming Wang
doaj   +1 more source

The HEAO-1 neutron star timing experiment [PDF]

open access: yes
The HEAO-1 neutron star timing experiment is presented. The scientific motivation for the experiment, the reasons for the choice of Her X-1 and Vela X-1 as promising sources to study, the methodology, and the current status of the experiment are ...
Lamb, F. K.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Patients’ Preferences for the Treatment of a Single Missing Tooth in China: A Discrete Choice Experiment

open access: yesPatient Preference and Adherence
Ming-yu Zhao,1,* Wen Zeng,2,* Sze Ngai Chan,3 Jianhao Du,4 Naman Rao,5 Taoran Liu,6 Wai-kit Ming6 1Department of Prosthodontics, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine ...
Zhao MY   +6 more
doaj  

Testing Choice Experiment for Benefit Transfer [PDF]

open access: yes
Benefit transfer is a cost-effective method for estimating the value of environmental goods that relies on information obtained in previous studies. The multi-attribute approach of choice experiment should provide advantages in terms of benefit transfer ...
Calatrava-Requena, Javier   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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