Results 101 to 110 of about 2,199,001 (304)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Improving the efficiency of individualized designs for the mixed logit choice model by including covariates. [PDF]

open access: yes
Recent research shows that the inclusion of choice related demo- and sociographics in discrete choice models aids in modeling the choice behavior of consumers substantially.
Crabbe, Marjolein, Vandebroek, Martina
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Impatience, Anticipatory Feelings and Uncertainty: A Dynamic Experiment on Time Preferences [PDF]

open access: yes
We study time preferences in a real-effort experiment with a one-month horizon. We report that two thirds of choices suggest negative time preferences. Moreover, choice reversal over time is common even if temptation plays no role. We propose and measure
Davide Dragone, Marco Casari
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Psychiatric nurses’ preferences for job: a discrete choice experiment

open access: yesBMC Nursing
Background Psychiatric nurses are instrumental in enhancing accessibility to care and addressing the mental health care needs of individuals. However, the field faces a significant shortage of nurses coupled with a high turnover rate. Developing policies
Hui-qin Li   +6 more
doaj   +1 more source

Targeting Consumers by Store - The Basis of Increased Sales with Less Advertising [PDF]

open access: yes
Conditional Logit approach was used to analyze the Choice Experiment data obtained from the grocery stores and supermarket of Tbilisi, Georgia. Results show that customers' preferences for selected pork attributes in different stores are not the same. So,
Foster, Kenneth A., Ubilava, David
core   +1 more source

Young's experiment and the finiteness of information

open access: yes, 2002
Young's experiment is the quintessential quantum experiment. It is argued here that quantum interference is a consequence of the finiteness of information.
A. Howie   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Delayed-choice gedanken experiments and their realizations

open access: yes, 2016
The wave-particle duality dates back to Einstein's explanation of the photoelectric effect through quanta of light and de Broglie's hypothesis of matter waves.
Kofler, Johannes   +2 more
core   +1 more source

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