Results 51 to 60 of about 10,439,347 (402)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

What Tinnitus Therapy Outcome Measures Are Important for Patients?– A Discrete Choice Experiment

open access: yesFrontiers in Neurology, 2021
Introduction: The therapeutic rationale varies among tinnitus therapies. A recent study identified which outcome measures should be used for different types of interventions.
Maaike M. Rademaker   +10 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Parent's preferences for unscheduled paediatric healthcare: A discrete choice experiment

open access: yesHealth Expectations, 2023
Background Unscheduled healthcare is a key component of healthcare delivery and makes up a significant proportion of healthcare access, with children being particularly high users of unscheduled healthcare.
Emma Nicholson   +5 more
doaj   +1 more source

Vaccine eagerness: A new framework to analyse preferences in single profile discrete choice experiments. Application to HPV vaccination decisions among French adolescents

open access: yesSSM: Population Health, 2022
Background: We previously conducted a single-profile discrete choice experiment to elicit preferences of adolescents around HPV vaccine communication, finding that only half of participants made variable choices (non-uniform respondents) from which ...
Sandra Chyderiotis   +38 more
doaj   +1 more source

Consumer behavior and corporate social responsibility: An evaluation by a choice experiment

open access: yesCorporate Social Responsibility and Environmental Management, 2018
The relationship between corporate social responsibility and consumer's behavior is more and more strong today: so it influences management of ethical and social effects of companies.
F. Boccia, Rosa Malgeri Manzo, D. Covino
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Determinates of farmer’s preference for watershed ecosystem services: The case of Belesa districts, Amhara region of Ethiopia”

open access: yesCogent Food & Agriculture, 2021
Watersheds provide diverse range of goods and services which are vital for the sustenance of human wellbeing. Despite the huge volume of watershed development work in the intervention sites, sustainable flow of benefits from the constructed structures ...
Yasin Ahmed, Erimase Tesfye
doaj   +1 more source

Should flavours be banned in cigarettes and e-cigarettes? Evidence on adult smokers and recent quitters from a discrete choice experiment

open access: yesTobacco Control, 2018
Objectives To provide the policy-relevant estimates of impacts of alternative flavour bans on preferences and demand for cigarettes and e-cigarettes in adult smokers and recent quitters.
John Buckell, J. Marti, J. Sindelar
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

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