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Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by strictures of the biliary tree complicated by cirrhosis and cholangiocarcinoma. It is immune mediated, although the precise aetiology remains unknown.Research into etiopathogenesis and epidemiology, diagnosis of cholangiocarcinoma, associations with inflammatory ...
Maggs, JR, Chapman, R
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Primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is an inflammatory disease of unknown etiology. It affects the biliary system and is characterized by fibrosis and progressive obliteration of extrahepatic and intrahepatic bile ducts. Its frequent coexistence with antibody-mediated diseases, certain human leukocyte antigens, and altered lymphocyte mechanisms ...
F M, Martin, J W, Braasch
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Secondary sclerosing cholangitis: mimics of primary sclerosing cholangitis
Sclerosing cholangitis is a chronic cholestatic disease characterized by stricturing, beading, and obliterative fibrosis of the bile ducts. Sclerosing cholangitis is considered primary (PSC) if no underlying etiology is identified or secondary (SSC) if related to another identifiable cause.
Daniel R. Ludwig+5 more
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CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
CAQ Corner: Immune‐mediated complications
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Primary sclerosing cholangitis [PDF]
Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by inflammatory destruction of the intrahepatic and/or extrahepatic bile ducts, leading to bile stasis, fibrosis, and ultimately to cirrhosis, and often requires liver transplantation (LT).
Marina Silveira, Anahita Rabiee
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Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by fibrosing inflammation and obliteration of intra- and/or extrahepatic bile ducts. The disease is one of the most common cholestatic diseases in adults and is diagnosed with increasing frequency. It is very often associated with ulcerative colitis. Patients with
Adolf Stiehl, C. Benz, Peter Sauer
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Primary Sclerosing Cholangitis [PDF]
Summary The literature on the subject of sclerosing cholangitis is reviewed. The value of conserving the gall bladder, of operative cholangiography and of the administration of steroids in the management of these patients is emphasized.
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MAIT cells come to the rescue in cancer immunotherapy? [PDF]
Recent progress in immunobiology has led to the observation that, among cells classically categorized as the typical representatives of the adaptive immune system, i.e., T cells, some possess the phenotype of innate cells.
Elewaut, Dirk+2 more
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