Results 51 to 60 of about 21,441 (140)

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source

Prevalence and risk factors for metabolic dysfunction–associated steatotic liver disease in Sweden: Insights from the SCAPIS cohort

Journal of Internal Medicine, EarlyView.
Abstract Background and Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disease globally, but its prevalence and severity remain poorly characterized in the general population. Our aim was to estimate the prevalence of MASLD and the risk of advanced fibrosis in a large Swedish general population ...
Oumarou Nabi, Jonas Spaak, Göran Bergström, Gunnar Engström, Carl Johan Östgren, Andrei Malinovschi, Joel Kullberg, Anders Blomberg, Tomas Jernberg, Daniel P. Andersson, Hannes Hagström   +10 more
wiley   +1 more source

Association Between Oral Lichen Planus and Non‐Oral Cancers: A Multicentre Case–Control SIPMO Study

Oral Diseases, EarlyView.
ABSTRACT Objectives This multicentre case–control study aimed to investigate the potential association between oral lichen planus (OLP) and extraoral cancers. The secondary objective included the identification of risk factors for this association. Methods The study was conducted between January 2023 and June 2024 and included 21 Italian Oral Medicine ...
Gioele Gioco, Anna Schiavelli, Alessandra Majorana, Elena Bardellini, Silvio Abati, Andrea Sardella, Francesco Spadari, Matteo Pellegrini, Dorina Lauritano, Raffaele Borgia, Monica Pentenero, Samuele Sutera, Paolo Giacomo Arduino, Alessio Gambino, Roberto Broccoletti, Matteo Biasotto, Giulia Ottaviani, Lorenzo Azzi, Alessandro D'Aiuto, Davide Bartolomeo Gissi, Andrea Gabusi, Andrea Santarelli, Marco Mascitti, Paolo Vescovi, Gloria Bortolotti, Maddalena Manfredi, Marco Meleti, Grazia Zino, Umberto Romeo, Gianluca Tenore, Gianfranco Favia, Luisa Limongelli, Massimo Petruzzi, Francesca Dimilito, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Giuseppina Campisi, Vera Panzarella, Stefania Leuci, Rosario Serpico, Alberta Lucchese, Giuseppe Colella, Giacomo Oteri, Antonia Marcianò, Gaetano Isola, Alessandro Polizzi, Amerigo Giudice, Elena Calabria, Umberto Mariani, Daniela Adamo, Federica Canfora, Filippo Graziani, Marco Nisi, Michele Giuliani, Luisa Ritrovato, Federica De Micheli, Cosimo Rupe, Francesco Scilla, Romeo Patini, Massimo Cordaro, Michele Davide Mignogna, Carlo Lajolo, SIPMO (Italian Society of Oral Pathology and Medicine)   +62 more
wiley   +1 more source

Dilation Device Use and Concomitant Antegrade Stenting are Associated With Procedure‐related Early Adverse Events After Endoscopic Ultrasound‐guided Hepaticogastrostomy: A Retrospective Multicenter Study

DEN Open, Volume 6, Issue 1, April 2026.
This multicenter study identified use of dilation devices and antegrade stenting are risk factors for procedure‐related early adverse events following endoscopic ultrasound‐guided hepaticogastrostomy. ABSTRACT Objectives Endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) is useful in cases of endoscopic retrograde cholangiopancreatography ...
Shinichi Hashimoto, Hiroki Taguchi, Norimasa Araki, Yu Yamazato, Hiroki Iwata, Yuji Tabira, Ryusuke Shibata, Yusuke Kamikihara, Koshiro Toyodome, Issei Kojima, Takafumi Hamada, Kengo Tsuneyoshi, Yoshitaka Nakamura, Hiroki Yano, Makoto Hinokuchi, Shiho Arima, Shiroh Tanoue, Fumisato Sasaki, Shuji Kanmura, Akio Ido   +19 more
wiley   +1 more source

Distal Bile Duct Metastasis From Rectal Cancer: The Diagnostic Contribution of Intraductal Ultrasonography

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 49‐year‐old male developed liver dysfunction during chemotherapy for rectal cancer located in the rectosigmoid region. Although magnetic resonance cholangiopancreatography initially indicated sclerosing cholangitis, endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed multiple non‐contiguous intraductal ...
Shinji Monoe, Ryo Nishio, Arihiro Nakano, Yu Yasue, Takahiro Yamashita, Hitoshi Iwata   +5 more
wiley   +1 more source

A Clinical Scoring Model to Predict Post‐Endoscopic Retrograde Cholangiopancreatography Pancreatitis in Biliary Endoscopic Retrograde Cholangiopancreatography for Patients With Intact Papilla: A Large Multicenter Prospective Cohort Study

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives The risk of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) needs to be predicted in order to take adequate preventive measures in individual cases. The aim of this study was to develop a clinical prediction rule for PEP in biliary ERCP for patients with intact papilla.
Koichi Fujita, Shujiro Yazumi, Hisakazu Matsumoto, Masanori Asada, Hiroko Nebiki, Keiji Hanada, Kazuya Matsumoto, Toru Maruo, Mamoru Takenaka, Hideki Kamada, Chishio Noguchi, Hidefumi Nishikiori, Toshifumi Doi, Teru Kumagi, Takao Iemoto, Nobuaki Azemoto, Takashi Kawamura, Hirofumi Kawamoto, for the Bilio‐pancreatic Study Group of West Japan   +18 more
wiley   +1 more source

Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits

International Journal of Cancer, Volume 158, Issue 5, Page 1193-1203, 1 March 2026.
What's New? Hepatocellular carcinoma arises from a combination of environmental and genetic factors, with the latter playing a potentially more significant role in nonviral hepatocellular carcinoma. Here, the authors characterized the genetic correlations and heritability between nonviral hepatocellular carcinoma and 901 epidemiologic, behavioral, and ...
Younghun Han, Vikram R. Shaw, Jinyoung Byun, Aaron P. Thrift, Catherine Zhu, Donghui Li, Rikita I. Hatia, Robin Kate Kelley, Sean P. Cleary, Anna S. Lok, Paige M. Bracci, Jennifer B. Permuth, Roxana Bucur, Jennifer Knox, Jian‐Min Yuan, Amit G. Singal, Prasun K. Jalal, R. Mark Ghobrial, Yuko Kono, Dimpy P. Shah, Mindie H. Nguyen, Neehar D. Parikh, Richard Kim, Hui‐Chen Wu, Hashem El‐Serag, Ping Chang, Yun Shin Chun, Jian Gu, Chad Huff, Asif Rashid, Lu‐Yu Hwang, Alison P. Klein, Saira A. Khaderi, Ahmed O. Kaseb, Kathrine A. McGlynn, Lewis R. Roberts, Manal M. Hassan, Christopher I. Amos   +37 more
wiley   +1 more source

Increased incidence, survival, and registration quality of primary hepato‐pancreato‐biliary cancers in the Netherlands Cancer Registry

International Journal of Cancer, Volume 158, Issue 5, Page 1237-1249, 1 March 2026.
What's New? Primary hepato‐pancreato‐biliary cancers have poor prognosis and their reporting often scores low on standard data quality indicators in population‐based cancer registries. This comprehensive evaluation of cases in the Netherlands Cancer Registry shows that both the incidence and survival rates of most primary hepato‐pancreato‐biliary ...
Lydia G. van der Geest, Marianne van der Mark, Joanne Verheij, Arantza Farina Sarasqueta, Judith de Vos‐Geelen, Marc G. Besselink, Vincent E. de Meijer, Ignace H. J. T. de Hingh, Bert A. Bonsing, Philip R. de Reuver, Francois E. J. A. Willemssen, Pauline A. J. Vissers, Otto Visser, the Dutch Pancreatic Cancer Group and the Dutch Hepatocellular & Cholangiocarcinoma Group   +13 more
wiley   +1 more source

Excluding Ascites From the GEMA‐Na Score Does Not Impact Outcome Predictions in Liver Transplant Candidates

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background and Aims Although GEMA‐Na outperforms MELD 3.0 for liver allocation, concerns about the subjectivity of its ascites component persist. We compared the performance of a GEMA‐Na iteration that excludes ascites with other allocation scores.
Manuel Luis Rodríguez‐Perálvarez, Antonio Manuel Gómez‐Orellana, Avik Majumdar, Geoffrey W. McCaughan, María Kalafateli, Rhiannon Taylor, Gloria de la Rosa, María Victoria Aguilera, Mikel Gastaca, Carmen Cepeda‐Franco, María Luisa Ortiz, Jordi Colmenero, Alejandra Otero, Rocío González Grande, Alba Cachero, Esther Molina Pérez, Mónica Barreales, Rosa Martín Mateos, María Rodríguez‐Soler, Mario Romero, Cristina Dopazo, Carmen Alonso Martín, Elena Otón, Luisa González Diéguez, María Dolores Espinosa, Ana Arias Milla, Gerardo Blanco Fernández, Sara Lorente, Antonio Cuadrado Lavín, Miguel Sogbe, David Guijo‐Rubio, César Hervás Martínez, Emmanuel Tsochatzis   +32 more
wiley   +1 more source

Efficacy, Safety and Tolerability of Volixibat, an IBAT Inhibitor, in Patients With Intrahepatic Cholestasis of Pregnancy

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Intrahepatic cholestasis of pregnancy (ICP) presents with cholestatic pruritus, elevated sBA and increased risk of adverse perinatal outcomes. Volixibat is a minimally absorbed IBAT inhibitor that interrupts enterohepatic recirculation. We describe four patients with ICP with pruritus and sBA > ULN treated with volixibat (20 or 80 mg BID ...
Caroline Ovadia, Sophia Stone, Baha Sibai, Tiago Nunes, Douglas B. Mogul, Jayshree Krishnaswami, Jennifer Kahng, Furong Li, Qurratul Ann Warsi, Elaine Chien, Pamela Vig, Catherine Williamson   +11 more
wiley   +1 more source