Results 81 to 90 of about 35,855 (199)

Outcome After Surgery for Colon Cancer in a National Cohort of Patients With and Without Inflammatory Bowel Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
This national cohort study of patients surgically resected for colon cancer, during 2007–2021, compares survival outcomes of patients with and without inflammatory bowel diseases. The main results were that overall survival, recurrence‐free survival and cancer‐specific survival were lower in patients with IBD.
Erik Lundqvist, Karin Westberg, Sol Erika Boman, Ida H. Myrberg, Åsa H. Everhov, Pär Myrelid, Bengt Glimelius, Anna Martling, Caroline Nordenvall   +8 more
wiley   +1 more source

Adjustment of Surveillance Intervals for Ulcerative Colitis‐Associated Neoplasia Based on Disease Duration

Digestive Endoscopy, EarlyView.
ABSTRACT Objectives The risk of colitis‐associated cancer increases with disease duration in ulcerative colitis (UC), yet surveillance colonoscopy protocols generally stratify risk uniformly for patients with disease lasting over 8 years. This study evaluated whether shorter surveillance intervals might enhance lesion detection rates in patients with ...
Ryoya Sakakibara, Shinya Sugimoto, Yuta Kaieda, Hiroki Kiyohara, Yusuke Yoshimatsu, Kaoru Takabayashi, Soichiro Murakami, Miho Kawaida, Tomohisa Sujino, Naoki Hosoe, Motohiko Kato, Yasushi Iwao, Yohei Mikami, Takanori Kanai   +13 more
wiley   +1 more source

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

European Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano, Emmanuel Somm, François R. Jornayvaz, Nicolas Vuilleumier   +3 more
wiley   +1 more source

IgG4-related autoimmune disease : imaging findings [PDF]

, 2013
IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction ...
Vassallo, Pierre
core  

Branched‐chain amino acids and all‐cause mortality in patients with liver cirrhosis, and the onset of diabetes in liver transplant recipients

European Journal of Clinical Investigation, EarlyView.
Our study demonstrates that total BCAA levels increase following liver transplantation. In patients with cirrhosis, higher total BCAA levels are associated with a reduced risk of all‐cause mortality. However, while this association is not observed in liver transplant recipients, elevated total BCAA levels are strongly linked to an increased risk of new‐
Yakun Li, Mateo Chvatal‐Medina, Maria Camila Trillos‐Almanza, Margery A. Connelly, Han Moshage, Stephan J. L. Bakker, Vincent E. de Meijer, Hans Blokzijl, Robin P. F. Dullaart, TransplantLines Investigators   +9 more
wiley   +1 more source

Multi‐omic analysis identifies biological processes underlying progressive interstitial lung disease in systemic sclerosis

The FEBS Journal, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease, and lung complications (ILD) are the main cause of death. This study compared SSc patients with and without lung disease to healthy volunteers. We found increased inflammation, specific proteins, and higher triglyceride levels linked to lung disease progression. These findings suggest triglycerides
Selena Bouffette, Perrine Soret, Alice Cole, Emmanuel Nony, Pierre Barbier Saint Hilaire, Grégory Leclerc, Lamine Alaoui, Audrey Aussy, Isabelle Wehrle, Aude Le Gall, Mark Coulon, Marc Pallardy, Voon Ong, Jeanne Allinne, Philippe Moingeon, David Abraham, Christopher P. Denton   +16 more
wiley   +1 more source

Effect of Tirzepatide Treatment on Hepatic Biomarkers in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Type 2 Diabetes Mellitus

Hepatology Research, EarlyView.
This study evaluated the effects of tirzepatide in patients with Type 2 diabetes mellitus and metabolic dysfunction‐associated steatotic liver disease. After 48 weeks of treatment, patients showed significant improvements in liver steatosis and injury, surrogate markers of liver fibrosis, glycemic control, and body weight. ABSTRACT Aim This study aimed
Taeang Arai, Masanori Atsukawa, Chikako Nagao, Zento Yamada, Takahiro Rokugo, Kenta Suzuki, Michika Kitamura, Tetsuyuki Higashi, Kaori Koyano, Yuta Hasegawa, Tadamichi Kawano, Hiroki Ono, Yuji Yoshida, Tomomi Okubo, Korenobu Hayama, Ai Nakagawa‐Iwashita, Norio Itokawa, Chisa Kondo, Mototsugu Nagao, Masato Iwabu, Katsuhiko Iwakiri   +20 more
wiley   +1 more source

Bidirectional causal links between diabetes mellitus and autoimmune liver diseases: Insights from Mendelian randomization

Journal of Diabetes Investigation, EarlyView.
This study employed a two‐sample Mendelian randomization approach to assess the causal relationship between autoimmune liver diseases (AILD) and diabetes mellitus. We found that genetic predispositions to primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) were significantly associated with an increased risk of type 1 diabetes ...
Haixia Kuang, Jian Wu, Tao Huang, Kai Yan, Xiaoyun Hu, Ying Wu, Yudi Wang, Zhihong Wu, Xiao Chen, Gaole Yuan   +9 more
wiley   +1 more source

The Prognostic Value of the XPC rs2228001 Single Nucleotide Polymorphism in Cholangiocarcinoma

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Cholangiocarcinoma (CCA) is one of the most prevalent primary liver malignancies with increasing incidence and mortality rates, particularly in Southeast Asia. Surgical resection is a primary therapeutic option offered to patients with localised disease. Unfortunately, early disease recurrence is common and robust tools for
Guanwu Wang, Anna Mantas, Dong Liu, Tarick M. Al‐Masri, Smiths Sengkwawoh Lueong, Jens Siveke, Tom Luedde, Tom F. Ulmer, Iakovos Amygdalos, Florian W. R. Vondran, Georg Lurje, Ulf Peter Neumann, Lara R. Heij, Jan Bednarsch   +13 more
wiley   +1 more source

The great pretender : Autoimmune Pancreatitis [PDF]

, 2014
Autoimmune pancreatitis is a benign disorder which frequently presents with symptoms and imaging suggestive of pancreatic malignancy. Up to 21% of pancreatoduodenectomies performed for suspected pancreatic cancer are found to have benign disease ...
Azzopardi, Neville
core