Results 131 to 140 of about 124,517 (353)

Human epididymis protein 4 (HE4) in benign and malignant diseases [PDF]

open access: yes, 2012
Background: Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign ...
Anastasi   +39 more
core   +1 more source

Alterations of the bile microbiome in primary sclerosing cholangitis

open access: yesGut, 2019
Background Patients with primary sclerosing cholangitis (PSC) display an altered colonic microbiome compared with healthy controls. However, little is known on the bile duct microbiome and its interplay with bile acid metabolism in PSC.
T. Liwinski   +17 more
semanticscholar   +1 more source

Inflammatory Bowel Disease and Primary Sclerosing Cholangitis: A Review of the Phenotype and Associated Specific Features

open access: yesGut and Liver, 2018
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic disease that is associated with inflammatory bowel disease (IBD) in approximately 70% of cases.
Carolina Palmela   +4 more
doaj   +1 more source

Primary sclerosing cholangitis

open access: yesMedicine, 1984
Primary sclerosing cholangitis (PSC) is a chronic, cholestatic liver disease caused by diffuse inflammation and fibrosis that can involve the entire biliary tree. The progressive pathological process obliterates intrahepatic and extrahepatic bile ducts, leading ultimately to biliary cirrhosis, portal hypertension and hepatic failure.
openaire   +3 more sources

Massive infestation by Ascaris lumbricoides of the biliary tract: report of a successfully treated case Infestação maciça por Ascaris lumbricoides nas vias biliares: relato de um caso tratado com sucesso

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1992
This is a report of a 25 years old black woman from the city of São Paulo, Brazil, who developed acute obstructive cholangitis of Ascaris lumbricoides with septicemia and multiple hepatic abscesses. The patient had sickle cell trait and normal delivery 3
Dahir Ramos de Andrade Júnior   +6 more
doaj   +1 more source

Systematic review with meta‐analysis: risk factors for recurrent primary sclerosing cholangitis after liver transplantation

open access: yesAlimentary Pharmacology and Therapeutics, 2019
After liver transplantation primary sclerosing cholangitis (PSC), the condition returns in the transplanted liver in a subset of patients (recurrent primary sclerosing cholangitis, rPSC).
I. Steenstraten   +6 more
semanticscholar   +1 more source

Feline Cholangitis

open access: yesVeterinary Clinics of North America: Small Animal Practice
Inflammatory biliary tract disease (cholangitis) is the commonest liver disease in cats but remains poorly understood. There are chronic lymphocytic and acute neutrophilic forms together with chronic neutrophilic cholangitis which may overlap both these categories.
openaire   +2 more sources

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang   +5 more
wiley   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

open access: yesiNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen   +6 more
wiley   +1 more source

Validity of an Automated Algorithm to Identify Cirrhosis Using Electronic Health Records in Patients with Primary Biliary Cholangitis

open access: yesClinical Epidemiology, 2020
Mei Lu,1 Christopher L Bowlus,2 Keith Lindor,3 Carla V Rodriguez-Watson,4 Robert J Romanelli,5 Irina V Haller,6 Heather Anderson,7 Jeffrey J VanWormer,8 Joseph A Boscarino,9 Mark A Schmidt,10 Yihe G Daida,11 Amandeep Sahota,12 Jennifer Vincent,13 Jia Li ...
Lu M   +16 more
doaj  

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