Results 161 to 170 of about 70,191 (302)

Drug-Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion. [PDF]

open access: yesPharmacol Res Perspect
Barbaro LE   +7 more
europepmc   +1 more source

Pemafibrate Improves Cholestatic Markers Regardless of the Presence of Primary Biliary Cholangitis

open access: yesHepatology Research, EarlyView.
Pemafibrate improves liver function markers related to bile flow in primary biliary cholangitis (PBC), but whether this effect is disease‐specific remains unclear. In this study, pemafibrate reduced these markers in patients with and without PBC, suggesting broader effects on bile flow beyond PBC.
Ryohei Tanigawa   +5 more
wiley   +1 more source

Stability and Variability of Symptom Burden in Primary Biliary Cholangitis: Insights From a Decade of Follow‐Up

open access: yesHepatology Research, EarlyView.
Impairment of health‐related quality of life in patients with PBC, in particular observed in younger female, represents distinct dimensions of disease impact, independently of long‐term outcomes. Overall and interindividual changes in PBC‐40 scores greatly varied over 10 years, suggesting that symptom burdens are driven by heterogeneous underlying ...
Akihito Takeuchi   +22 more
wiley   +1 more source

Hepatic Carcinoma With Epithelial–Myoepithelial Differentiation and Metachronous Intrahepatic Recurrence Following Curative Resection: A Rare Case Report

open access: yesHepatology Research, EarlyView.
ABSTRACT Background and Aim Epithelial‐myoepithelial carcinoma (EMC), a malignant tumor with biphasic epithelial and myoepithelial differentiation, is typically a salivary gland neoplasm. Contrastingly, myoepithelial carcinoma (MEC) predominantly comprises myoepithelial cells.
Ryo Nagao   +13 more
wiley   +1 more source

Histological AI‐Assisted Analysis Outperforms Pathologist Assessment in Predicting Disease Outcomes in PSC Patients

open access: yesHepatology Research, EarlyView.
Analyzing liver histology with AI assistance demonstrates superior prognostic performance compared to manual scoring in PSC. AI‐measured portal inflammation, fibrosis, biliary epithelium, and blood vessels predicted key clinical endpoints, such as liver transplantation due to end‐stage liver disease, highlighting the importance of liver histology as a ...
Anna M. Salonen   +9 more
wiley   +1 more source

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

open access: yesHepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura   +10 more
wiley   +1 more source

First Case Report of Triple Recurrent Cholangitis of "Coildocholithiasis," Following Hepatic Artery Pseudoaneurysm Embolization. [PDF]

open access: yesDEN Open
Nishihara S   +9 more
europepmc   +1 more source

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