Results 191 to 200 of about 101,142 (261)

Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis.

New England Journal of Medicine, 2023
BACKGROUND Primary biliary cholangitis is a rare, chronic cholestatic liver disease characterized by the destruction of interlobular bile ducts, leading to cholestasis and liver fibrosis.
Kris V. Kowdley, C. Bowlus, Cynthia Levy, U. Akarca, M. Álvares-da-Silva, P. Andreone, M. Arrese, C. Corpechot, Sven M. Francque, M. Heneghan, P. Invernizzi, David Jones, F. Kruger, E. Lawitz, M. Mayo, M. Shiffman, M. Swain, J. M. Valera, V. Vargas, J. Vierling, A. Villamil, Carol Addy, J. Dietrich, J. Germain, Sarah Mazain, D. Rafailovic, Bachirou O Taddé, Benjamin Miller, J. Shu, C. Zein, J. Schattenberg   +30 more
semanticscholar   +1 more source

Acute cholangitis: current concepts [PDF]

ANZ Journal of Surgery, 2017
BACKGROUND: Acute cholangitis, also known as ascending cholangitis, is a life-threatening systemic condition that results from a biliary tree infection and obstruction.
Christopher Christophi, Vijayaragavan Muralidharan   +1 more
exaly   +2 more sources

New Treatment Paradigms in Primary Biliary Cholangitis.

Clinical Gastroenterology and Hepatology, 2023
Primary biliary cholangitis (PBC) is an archetypal autoimmune disease. Chronic lymphocytic cholangitis is associated with interface hepatitis, ductopenia, cholestasis and a progressive biliary fibrosis.
C. Levy, Michael M. Manns, G. Hirschfield   +2 more
semanticscholar   +1 more source

Incidence and Prevalence of Primary Sclerosing Cholangitis: A Meta-analysis of Population-based Studies.

Inflammatory Bowel Diseases, 2023
BACKGROUND Primary sclerosing cholangitis is a chronic liver disease associated with significant morbidity, mortality, and healthcare utilization.
Jared L. Cooper, A. Markovinović, S. Coward, M. Herauf, A. Shaheen, Mark G. Swain, R. Panaccione, Christopher Ma, Cathy Lu, Kerri L. Novak, K. Kroeker, S. Ng, G. Kaplan   +12 more
semanticscholar   +1 more source

IgG4-associated cholangitis: a comparative histological and immunophenotypic study with primary sclerosing cholangitis on liver biopsy material

Modern Pathology, 2009
IgG4-associated cholangitis is a steroid-responsive hepatobiliary inflammatory condition associated with autoimmune pancreatitis that clinically and radiologically mimics primary sclerosing cholangitis.
Vikram Deshpande, Nisha I Sainani, Raymond T Chung   +2 more
exaly   +2 more sources

Cholangitis

World Journal of Surgery, 1984
AbstractComparative study of the clinical features of 125 cases of acute cholangitis revealed that acute obstructive suppurative cholangitis (AOSC, 19 cases) was characterized by leukocytosis, high transaminase levels, bilirubinemia, and a marked thrombocytopenia. Most species of bacilli isolated from the purulent bile were gram‐negative and in 9 of 12
H, Kinoshita, K, Hirohashi, S, Igawa, E, Nagata, K, Sakai   +4 more
openaire   +2 more sources

Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

Gut, 2021
Objective Multiple clinical similarities exist between IgG4-related sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC), and while gut dysbiosis has been extensively studied in PSC, the role of the gut microbiota in IgG4-SC remains ...
Qiaoyan Liu, Bo Li, Yikang Li, Yiran Wei, Bingyuan Huang, Jubo Liang, Z. You, You Li, Qiwei Qian, Rui Wang, Jun Zhang, Ruiling Chen, Zhuwan Lyu, Yong Chen, M. Shi, Xiao Xiao, Qixia Wang, Q. Miao, J. Fang, M. Gershwin, M. Lian, Xiong Ma, R. Tang   +22 more
semanticscholar   +1 more source

Primary sclerosing cholangitis and obliterative cholangitis

The American Journal of Surgery, 1969
Abstract Idiopathic primary sclerosing cholangitis is but one type of generalized obliterative disease of the Table I Suggested Therapy in Primary Sclerosing Cholangitis and Obliterative Cholangitis Disease Operation Supportive Therapy Primary sclerosing cholangitis Bypass procedure, cholecysto-jejunostomy, Roux-en-y choledocho ...
B, Cutler, G A, Donaldson
openaire   +2 more sources

Sclerosing cholangitis

Baillière's Clinical Gastroenterology, 1997
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic liver disease whose aetiopathogenesis is unknown. PSC is frequently associated with inflammatory bowel disease, in particular chronic ulcerative colitis, is most commonly observed in young males and is clinically characterized by fatigue, pruritus and jaundice.
P J, Marotta, N F, LaRusso, R H, Wiesner
openaire   +2 more sources