Results 211 to 220 of about 101,142 (261)

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

American Journal of Gastroenterology, 2019
Cholestatic liver diseases encompass a broad spectrum of pathologies, with the core injury occurring at the level of cholangiocytes and progressing to hepatic fibrosis and liver dysfunction. Primary biliary cholangitis and primary sclerosing cholangitis are the most significant progressive cholangiopathies in adults. Although rare, they commonly evolve
Raquel T, Yokoda, Elizabeth J, Carey
openaire   +2 more sources

Fecal Microbiota Transplantation in Patients With Primary Sclerosing Cholangitis: A Pilot Clinical Trial.

American Journal of Gastroenterology, 2019
BACKGROUND Primary sclerosing cholangitis (PSC) is a cholestatic liver disease with no effective medical therapies. A perturbation of the gut microbiota has been described in association with PSC, and fecal microbiota transplantation (FMT) has been ...
J. Allegretti, Z. Kassam, Madeline Carrellas, B. Mullish, J. Marchesi, A. Pechlivanis, Mark Smith, Y. Gerardin, Sonia C. Timberlake, D. Pratt, J. Korzenik   +10 more
semanticscholar   +1 more source

IgG4-Associated Cholangitis

Digestive Diseases, 2014
IgG4-associated cholangitis (IAC) is the hepatobiliary manifestation of immunoglobulin G4-related disease (IgG4-RD), a systemic fibroinflammatory disorder with a wide variety of clinical presentations and organ manifestations. IgG4-RD predominantly affects the hepatobiliary tract (IAC) and pancreas (autoimmune pancreatitis) and mimics hepatobiliary ...
Beuers, Ulrich, Maillette de Buy Wenniger, Lucas J., Doorenspleet, Marieke, Hubers, Lowiek, Verheij, Joanne, van Gulik, Thomas, van de Graaf, Stan F. J., de Vries, Niek   +7 more
openaire   +2 more sources

Primary Biliary Cholangitis

Current treatment options in gastroenterology, 2022
Andrew R. Scheinberg, Cynthia Levy
semanticscholar   +1 more source

Primary sclerosing cholangitis

The Lancet, 2018
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis.

semanticscholar   +1 more source

Ischemic Cholangitis

Mayo Clinic Proceedings, 1998
Ischemia-induced bile duct lesions have been collectively labeled as ischemic cholangitis. The biliary epithelium is dependent on arterial blood flow, unlike the hepatic parenchyma with its dual arterial and portal venous blood supply. As such, the biliary epithelium is susceptible to injury when arterial blood flow is compromised.
openaire   +2 more sources

EASL Clinical Practice Guidelines on Sclerosing Cholangitis.

Journal of Hepatology, 2022
O. Chazouilleres, U. Beuers, A. Bergquist, T. Karlsen, C. Levy, M. Samyn, C. Schramm, M. Trauner   +7 more
semanticscholar   +1 more source

ACUTE CHOLANGITIS

Infectious Disease Clinics of North America, 1992
Acute cholangitis is a clinical syndrome marked by fever, jaundice, and abdominal pain that develops because of stasis and infection in the biliary tract. Patients with cholangitis may present with symptoms ranging from a mild, recurrent illness to overwhelming sepsis.
openaire   +2 more sources

Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study.

The Lancet Gastroenterology and Hepatology, 2019
BACKGROUND The aim of this study was to evaluate the long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis using 3-year interim data from the 5-year open-label extension of the pivotal phase 3 POISE trial ...
M. Trauner, F. Nevens, M. Shiffman, J. Drenth, C. Bowlus, V. Vargas, P. Andreone, G. Hirschfield, R. Pencek, E. Malecha, L. Macconell, D. Shapiro   +11 more
semanticscholar   +1 more source

The Pathogenesis of Primary Biliary Cholangitis: A Comprehensive Review

Seminars in liver disease (Print), 2019
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by autoimmune destruction of small to medium size intrahepatic bile ducts. The etiology of PBC remains unknown and pathogenesis features immune-mediated biliary injury,
A. Lleo, P. Leung, G. Hirschfield, E. Gershwin   +3 more
semanticscholar   +1 more source