Results 61 to 70 of about 93,225 (309)
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin+50 more
wiley +1 more source
Inflammatory biliary tract disease (cholangitis) is the commonest liver disease in cats but remains poorly understood. There are chronic lymphocytic and acute neutrophilic forms together with chronic neutrophilic cholangitis which may overlap both these categories.
openaire +2 more sources
ABSTRACT Background Chyle leak (CL) is a relevant complication of pancreatic surgery, but its incidence, risk factors, clinical and oncologic impacts, and nutritional relevance remain inconsistent and limited. Methods We retrospectively reviewed patients who underwent pancreaticoduodenectomy for pancreatic head cancer from 2007 to 2023 at a single ...
Jae Seung Kwak+4 more
wiley +1 more source
ABSTRACT Background This study aimed to evaluate the outcomes of patients with unresectable cholangiocarcinoma (CCA) who underwent portal vein embolization (PVE) with a focus on overall survival (OS) and the frequency of biliary drainage (BD). Methods In this retrospective analysis, we evaluated 255 patients with unresectable CCA; 56 patients underwent
Ho Seung Lee+8 more
wiley +1 more source
ABSTRACT Background We aimed to investigate the microbiological characteristics of pathogens isolated from blood cultures (BCs) of patients with acute cholangitis (AC) after biliary‐enteric anastomosis and biliary intervention (BI). Methods A retrospective analysis was conducted on 366 patients with AC and bacteremia between 2015 and 2024 at Hiroshima ...
Yuta Kuhara+9 more
wiley +1 more source
A Common Variant in CLDN14 is Associated with Primary Biliary Cirrhosis and Bone Mineral Density. [PDF]
Primary biliary cirrhosis (PBC), a chronic autoimmune liver disease, has been associated with increased incidence of osteoporosis. Intriguingly, two PBC susceptibility loci identified through genome-wide association studies are also involved in bone ...
Bian, Zhaolian+18 more
core +2 more sources
ABSTRACT Background Lymph node (LN) metastasis in extrahepatic cholangiocarcinoma (eCCA) is associated with poor prognosis, but the impact of specific metastatic sites is unclear. This study investigated the clinical significance of LN metastasis around the common hepatic artery (N [CHA]) in eCCA.
Sho Kiritani+9 more
wiley +1 more source
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine+24 more
wiley +1 more source
Abstract Objectives Pediatric acute pancreatitis (AP) is a growing clinical concern with a wide spectrum of severity, from mild episodes to life‐threatening conditions. Traditional diagnostic methods primarily rely on serum amylase and lipase measurements, which are invasive and can be challenging in children.
Tamar Orgad+8 more
wiley +1 more source
Advances in prognostic biomarkers for biliary atresia: Current insights and future directions
Abstract Biliary atresia (BA) is a progressive, fibrosing cholangiopathy of infancy characterized by inflammatory obstruction of the bile ducts, ultimately leading to end‐stage liver disease if untreated. Early diagnosis and timely surgical intervention via hepatoportoenterostomy (HPE) are critical for improving outcomes; however, prognostication ...
Ahmad Anouti+6 more
wiley +1 more source