Results 61 to 70 of about 25,411 (289)

A new metabolic path in type 3 rickets

The FEBS Journal, EarlyView.
Rickets, a bone disorder, was historically categorised into either nutritional (vitamin D deficiency) or genetic forms involving loss‐of‐function mutations in mineral metabolism. Recently, a new mechanism, type 3 rickets, was discovered to be caused by a gain‐of‐function mutation in CYP3A4 (Ile301Thr).
Toshiya Senda, Yoshihisa Hirota
wiley   +1 more source

The role of Cholecalciferol in the Improvement of Insulin Resistance in Diabetic Mice Model

Journal of Agromedicine and Medical Sciences (AMS), 2017
Insulin resistance is an important predictor of the incidence of diabetes mellitus. Vitamin D deficiency is one of the risk factors for insulin resistance, and there is a relationship between hypovitaminosis vitamin D with the prevalence of diabetes ...
Elly Nurus Sakinah
doaj   +1 more source

Perspectives of Older Patients on the Complexity of Medication Use

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Medication use complexity is associated with non‐adherence, hospitalizations, and lower quality of life. It is most frequently measured with the Medication Regimen Complexity Index (MRCI). This instrument estimates the complexity of a patient's medication regimen, taking into account the pharmaceutical dosage forms and routes ...
Charlotte M. Falke, Mariëlle F. J. Koolen, Samuel L. Timmer, Fatma Karapinar‐Çarkit, Marcel L. Bouvy, Antoine C. G. Egberts, Wilma Knol   +6 more
wiley   +1 more source

Metabolism of cholecalciferol in land snails [PDF]

Biochemical Journal, 1979
1. Radioactively labelled cholecalciferol was injected into the land snails Levantina hiersolyma and Theba pisana. Three metabolites (C, D and E), more polar than cholecalciferol, were found. 2. Metabolite C was found to be identical with 25-hydroxycholecalciferol.
S, Weiner, D, Noff, M S, Meyer, Y, Weisman, S, Edelstein   +4 more
openaire   +2 more sources

Effect of cholecalciferol on serum hepcidin and parameters of anaemia and CKD-MBD among haemodialysis patients: a randomized clinical trial

Scientific Reports, 2020
In this multicentre double-blind randomized clinical trial, we investigated the effects of oral cholecalciferol supplementation on serum hepcidin and parameters related to anaemia and CKD-MBD among haemodialysis patients.
Y. Obi, Satoshi Yamaguchi, T. Hamano, Y. Sakaguchi, Akihiro Shimomura, Tomoko Namba-Hamano, S. Mikami, O. Nishi, Motoko Tanaka, Akihito Kamoto, Yasue Obi, N. Tomosugi, Y. Tsubakihara, Y. Isaka   +13 more
semanticscholar   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

Efficacy of plain cholecalciferol versus ergocalciferol in raising serum vitamin D level in Thai female healthcare workers

Osteoporosis and Sarcopenia, 2022
Objectives: To compare the efficacy of cholecalciferol and ergocalciferol in raising 25-hydroxyvitamin D (25(OH)D) level in Thai female healthcare workers.
Tanawat Amphansap, Atiporn Therdyothin, Nitirat Stitkitti, Lertkong Nitiwarangkul, Vajarin Phiphobmongkol   +4 more
doaj   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

Orthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos, Georgios Kalinterakis, Pierrenzo Pozzi, Dimitris Fligkos, George Themistocleous, Sotirios Themistokleous, Triantafyllia Dimou, Riccardo Compagnoni, Paolo Ferrua, Pietro Simone Randelli   +9 more
wiley   +1 more source

Incorporation of oxygen-18 into the 25-position of cholecalciferol by hepatic cholecalciferol 25-hydroxylase [PDF]

Biochemical Journal, 1978
The oxygen enzymically inserted as a hydroxy function by rat liver post-mitochondrial fraction into the 25-position of cholecalciferol to giver 25-hydroxycholecaliferol is derived exclusively from molecular O2. Therefore like the other two cholecalciferol hydroxylases, i.e.
T C, Madhok, H K, Schnoes, H F, DeLuca
openaire   +2 more sources