Results 61 to 70 of about 25,487 (202)

Association of Aspirin With Improved Clinical Outcomes and Survival in Patients With Compensated Cirrhosis: A Propensity Score‐Matched Study of 25 782 Individuals

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Pharmacologic therapies to prevent decompensation in cirrhosis remain limited. Aim To evaluate the association between aspirin use and cirrhosis‐related outcomes and mortality. Methods This retrospective cohort study utilized deidentified electronic health records from a global federated network (January 2013–July 2025). Adults with
Shahem Abbarh   +6 more
wiley   +1 more source

Cholelithiasis in Thalassemia Major Patients: A Report from the South-East of Iran

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2018
Background: Cholelithiasis and its predisposing factors are less characterized in thalassemia syndromes. In the present study, we assessed the prevalence of gallstones and related-risk factors among thalassemia major (TM) patients in south-east of Iran ...
Iraj Shahramian   +5 more
doaj  

Gallbladder-Related Adverse Events With Semaglutide 2.4 mg: Pooled Analysis of Placebo-Controlled STEP Trials. [PDF]

open access: yesDiabetes Obes Metab
Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9701-9703, October 2026.
Ukkonen M   +5 more
europepmc   +2 more sources

GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati   +12 more
wiley   +1 more source

Intraoperative cholangiography during open cholecystectomy in 73 dogs with benign gallbladder disease

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To evaluate intraoperative cholangiography (IOC) during open cholecystectomy in dogs with benign gallbladder disease, including cases with preoperative common bile duct (CBD) obstruction, and to describe the short‐term outcomes. Study design Retrospective case series. Animals A total of 73 client‐owned dogs.
Ryusei Konno   +7 more
wiley   +1 more source

Balloon Enteroscopy‐assisted Endoscopic Retrograde Cholangiopancreatography for Choledocholithiasis in Situs Inversus Totalis With Billroth II Reconstruction: A Case Report and Literature Review

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic retrograde cholangiopancreatography (ERCP) in patients with situs inversus totalis (SIT) and Billroth II reconstruction is technically challenging because of mirror‐image anatomy, altered access to the papilla, and inverted papillary orientation.
Shuhei Shintani   +6 more
wiley   +1 more source

Quantitative Systems Toxicology Model Predicts Obeticholic Acid‐Associated Liver Injury in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1358-1367, November 2026.
Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving supratherapeutic OCA doses (100–250 mg).
Abigail K. Mayo   +4 more
wiley   +1 more source

Risk factors associated with symptomatic cholelithiasis in Taiwan: a population-based study

open access: yesBMC Gastroenterology, 2011
Background Cholelithiasis has become a major health problem in Taiwan. The predominant type of gallstone found in Asian populations differs from that in the West, indicating possible differences in the etiology and risk factors for cholelithiasis.
Lai Shih-Wei   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy