Results 51 to 60 of about 25,487 (202)

A 52‐Week Efficacy and Safety Study of Teneligliptin, as an Add‐On to Empagliflozin and Metformin in Patients With Type 2 Diabetes Mellitus: A Randomised, Double‐Blind, Placebo‐Controlled Phase 3 Trial (TERA305 Study)

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the long‐term efficacy and safety of teneligliptin add‐on in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin. Materials and Methods In this randomised, double‐blind, phase 3 trial, 214 patients received teneligliptin 20 mg (n = 107) or placebo (n = 107) once daily for 24 ...
Jun Sung Moon, Kyung Ah Han, Dong‐Lim Kim, Sang Yong Kim, Soo‐Kyung Kim, Bon Jeong Ku, Woo Je Lee, Tae Keun Oh, Ji A Seo, Sang‐Ah Chang, Moon‐Kyu Lee, Kyu Jeung Ahn, Chul Sik Kim, Tae Nyun Kim, Bong‐Soo Cha   +14 more
wiley   +1 more source

Association of fatty acid composition of blood serum with bile lipid composition in cholelithiasis patients

Терапевтический архив, 2008
Aim. To examine correlations between bile lipid composition and fatty acid composition of blood serum in cholelithiasis patients. Material and methods.
V V Tsukanov, E Iu Kupershteĭn, Iu L Tonkikh, E P Bronnikova   +3 more
doaj  

Clinical and instruments criterias of the correction effectiveness in patients with chronic opisthorchosis of cholelithiasis

Бюллетень сибирской медицины, 2009
To study influence of therapy Biltritsid and Ursosan on existence of cholelithiasis at opisthorchosis. Are inspected 87 patients with the cholelithiasis and chronic opisthorchosis.
A. L. Korkin
doaj   +1 more source

Severe chronic neutrophilic cholangiohepatitis with massive choledocholithiasis and hepatolithiasis in a pony

Equine Veterinary Education, EarlyView.
Summary A 20‐year‐old Camargue pony mare was referred for acute‐onset neurological signs and intermittent colic. Clinical examination revealed obtundation, cranial nerve deficits, head pressing, ventral strabismus and ataxia. Laboratory analyses showed marked hyperammonaemia, hyperbilirubinemia, severe increases in liver enzymes, hypoalbuminaemia and ...
C. Maino, N. Ellero, M. Morini, L. V. Muscatello, S. Sabattini, G. Bettini   +5 more
wiley   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Dietary patterns, genetic predisposition, and risk of cholelithiasis: a large-scale prospective cohort study

Frontiers in Nutrition
BackgroundLimited epidemiological evidence exists concerning the impact of healthy dietary patterns on reducing the risk of cholelithiasis. We aimed to examine the association of seven established dietary patterns with subsequent cholelithiasis risk and ...
Kecheng Jin, Kecheng Jin, Ningning Mi, Ningning Mi, Wangping He, Wangping He, Ruyang Zhong, Ruyang Zhong, Boru Jin, Boru Jin, Zhen Liu, Zhen Liu, Chunlu Dong, Chunlu Dong, Yanyan Lin, Yanyan Lin, Ping Yue, Ping Yue, Bin Xia, Qiangsheng He, Jinqiu Yuan, Wenbo Meng, Wenbo Meng   +22 more
doaj   +1 more source

Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis

Hepatology Research, EarlyView.
ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose, Kota Tsuruya, Yusuke Mishima, Yoshitaka Arase, Koichi Shiraishi, Vu Thi Hao, Satsuki Ieda, Masayuki Tanaka, Sanae Isaki, Tatehiro Kagawa   +9 more
wiley   +1 more source

Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous

Histopathology, EarlyView.
IDH1 mutations are spatially homogeneous in intrahepatic cholangiocarcinoma. Single‐sample molecular testing is sufficient for clinical decision‐making. Introduction IDH1 mutations occur in approximately 10%–20% of intrahepatic cholangiocarcinoma (iCCA) and constitute an established target for molecularly guided therapy.
Sharon Weidmann, Silvana Ebner, Aayushi Srivastava, Armin Wiegering, Stefan Zeuzem, Peter J. Wild, Maximilian N. Kinzler, Melanie C. Winter, Dirk Walter   +8 more
wiley   +1 more source

Cholelithiasis in Children: A Diagnostic and Therapeutic Approach

Journal of Pediatrics Review, 2017
Context: Although cholelithiasis is not a common condition in children, recent studies have documented an increasing incidence rate, owing to the development of diagnostic tools. The prevalence of cholelithiasis in children has been reported to be 0.13% -
Hasan Karami, Hamid Reza Kianifar, Shahryar Karami   +2 more
doaj  

The roles of lifestyle factors and genetic risk in the association between night shift work and cholelithiasis: a prospective cohort study

Frontiers in Endocrinology
BackgroundNight shift work has been associated with adverse health outcomes. Whether night shift work is associated with cholelithiasis remains uncertain, and the roles of genetic risk and lifestyle factors in cholelithiasis risk are unclear.MethodsWe ...
Wangping He, Wangping He, Ningning Mi, Ningning Mi, Kecheng Jin, Kecheng Jin, Boru Jin, Boru Jin, Ruyang Zhong, Ruyang Zhong, Zhen Liu, Zhen Liu, Yanyan Lin, Yanyan Lin, Hengwei Zhang, Hengwei Zhang, Ping Yue, Ping Yue, Bin Xia, Qiangsheng He, Jinqiu Yuan, Wenbo Meng, Wenbo Meng   +22 more
doaj   +1 more source