Results 51 to 60 of about 31,169 (238)

The relative risk of clinically relevant cholelithiasis among glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus, real-world study

Diabetology & Metabolic Syndrome
Background and Aim The association between biliary disorders with weight reduction enhanced by GLP-1RAs was observed frequently, nevertheless, the relative risk of the clinically relevant cholelithiasis was not specified clearly among different GLP-1RAs.
Mohammed Ali Gameil, Elshahat Ali Ahmed Mohamed Yousef, Rehab Elsayed Marzouk, Mohamed H. Emara, Abeer H. Abdelkader, Rasha Ibrahim Salama   +5 more
doaj   +1 more source

Antenatal diagnosis of fetal cholelithiasis

, 2010
Fetal cholelithiasis is extremely rare and there are few reported cases in the literature. Most cases are thought to develop in late pregnancy and while some may be identified during a third trimester scan, others will remain undetected.
Hazel Edwards, Sally Holloway
core   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Cost‐Effectiveness of Laparoscopic Common Bile Duct Exploration Versus Endoscopic Retrograde Cholangiopancreatography in Emergency Stone Management

ANZ Journal of Surgery, EarlyView.
Among 337 patients undergoing emergency management of common bile duct stones, laparoscopic common bile duct exploration was associated with lower healthcare costs, fewer procedures and shorter hospital stays than ERCP‐based management, supporting single‐stage surgical management as a safe and cost‐effective treatment strategy.
Tess Howard, Lily Owens, Harendra Maneesha De Silva, Darren Lowen, David Bird, Russell Hodgson   +5 more
wiley   +1 more source

Frequency of Cholelithiasis in Patients with Chronic Liver Disease: A Hospital-Based Study [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2016
Background and study aim: Liver Cirrhosis is a strong and a common known risk factor for Cholelithiasis. Cholelithiasis is a multifactorial disease, based on a complex interaction of environmental and genetic factors.
Mona Abdelmaksoud, Hoda El-Hady, Hussein Ahmed, Bihery Ahmed, Hala Hussein, Mostafa El-Shamy   +5 more
doaj   +1 more source

Long‐Term Safety and Efficacy of Obeticholic Acid in Patients With Primary Biliary Cholangitis: Final Results of the POISE Long‐Term Safety Extension

Alimentary Pharmacology &Therapeutics, EarlyView.
In the POISE open‐label extension, patients with primary biliary cholangitis with inadequate response or intolerance to ursodeoxycholic acid received long‐term obeticholic acid (OCA) treatment. Findings demonstrated a safety profile consistent with the known characteristics of OCA, with no unexpected safety signals, while supporting sustained efficacy ...
Christopher L. Bowlus, Frederik Nevens, Kris V. Kowdley, Alan Bonder, Thomas Capozza, Jing Li, Radhika Nair, Michael Trauner, David E. Jones   +8 more
wiley   +1 more source

The role of inflammatory proteins in mediating the effect of cathepsins on cholelithiasis: A mendelian randomization study

Science Progress
Objective Previous studies have suggested potential associations between cathepsins and cholelithiasis. This study aimed to investigate the potential causal relationships among cathepsins, inflammatory proteins, and cholelithiasis using Mendelian ...
Tong Yuan, Ting Wang
doaj   +1 more source

Concomitant Lemierre's Syndrome and Base-of-Skull Osteomyelitis Caused by <i>Arcanobacterium haemolyticum</i>, Complicated by Ceftriaxone-Associated Cholecystitis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Lemierre's syndrome and base‐of‐skull osteomyelitis can occur together in immunocompetent adolescents with Arcanobacterium haemolyticum bacteraemia. Prolonged high‐dose ceftriaxone may precipitate symptomatic cholecystitis. Clinicians should consider A.
Lane A, Stewart A.
europepmc   +2 more sources

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source