Results 111 to 120 of about 646,053 (288)
Quantitative prediction of multivalent ligand–receptor binding affinities for influenza, cholera, and anthrax inhibition [PDF]
Multivalency achieves strong, yet reversible binding by the simultaneous formation of multiple weak bonds. It is a key interaction principle in biology and promising for the synthesis of high-affinity inhibitors of pathogens. We present a molecular model
Liese, Susanne, Netz, Roland R.
core +2 more sources
Human Vaccines in India: Present and Future Perspectives
Vaccines are formulations that equip the human immune system to fight against a pathogen. All the vaccines approved for use are safe. On vaccination, the body produces enough clonal B and T cells to resist infection.
Prasanta Kumar Ghosh
doaj +1 more source
Vaccines against gastroenteritis, current progress and challenges
Enteric viral and bacterial infections continue to be a leading cause of mortality and morbidity in young children in low-income and middle-income countries, the elderly, and immunocompromised individuals.
Hyesuk Seo, Qiangde Duan, Weiping Zhang
doaj +1 more source
ABSTRACT Approximately 755 million cases and 7 million deaths have been reported since the COVID‐19 pandemic. Based on the availability of vaccines to contain the spread of COVID‐19, various vaccination plans have been implemented globally, some more effective than others, depending on each country's social, territorial, economic, and political ...
Marisol S. Romero‐Mancilla+2 more
wiley +1 more source
Directing diarrhoeal disease research towards disease-burden reduction [PDF]
Despite gains in controlling mortality relating to diarrhoeal disease, the burden of disease remains unacceptably high. To refocus health research to target disease-burden reduction as the goal of research in child health, the Child Health and Nutrition ...
Bhatnagar, Shinjini+10 more
core +3 more sources
Cost-effectiveness of new-generation oral cholera vaccines: a multisite analysis.
OBJECTIVES We evaluated the cost-effectiveness of a low-cost cholera vaccine licensed and used in Vietnam, using recently collected data from four developing countries where cholera is endemic.
M. Jeuland+4 more
semanticscholar +1 more source
Pandemic Prevention Paradigms: Understanding Global Health Governance
One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr+10 more
wiley +1 more source
Emerging Challenges and Opportunities in Infectious Disease Epidemiology. [PDF]
Much of the intellectual tradition of modern epidemiology stems from efforts to understand and combat chronic diseases persisting through the 20th century epidemiologic transition of countries such as the United States and United Kingdom.
Lewnard, Joseph A, Reingold, Arthur L
core
Estimation of vaccine efficacy in the presence of waning: application to cholera vaccines.
The authors present a nonparametric method for estimating vaccine efficacy as a smooth function of time from vaccine trials. Use of the method requires a minimum of assumptions.
L. Durham+5 more
semanticscholar +1 more source
Infectious Diseases Surveillance System in Nigeria: Lesson From COVID‐19 Pandemic
ABSTRACT Nigeria has experienced outbreaks of multiple infectious diseases, a major public health concern, in the last 10 years, including the Ebola virus in 2014, monkeypox in 2017, COVID‐19 in 2020, Lassa fever in 2022, measles in 2023, diphtheria in 2023, and the cholera outbreak in 2024.
Tolulope Joseph Ogunniyi+3 more
wiley +1 more source