Results 31 to 40 of about 16,673 (222)

Production of putative enhanced oral cholera vaccine strains that express toxin-coregulated pilus. [PDF]

open access: yesPLoS ONE, 2017
The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V.
Caitlyn A Hauke, Ronald K Taylor
doaj   +1 more source

The influence of immunomodulators on the formation of vaccine-induced cholera immunity

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2022
Introduction. Due to the remaining tense situation on cholera in the world, research continues on the creation of new preventive drugs, as well as ways to increase the immunogenicity of existing anti-cholera vaccines.
A. V. Filippenko   +3 more
doaj   +1 more source

Re-emergence of Cholera Vaccine [PDF]

open access: yesJournal of Travel Medicine, 1997
Although epidemic cholera was first described in 1817, the disease probably has been common in the Indian subcontinent since ancient times.1 Until recently, a single bacterial type (Vibrio cholerae 01) has been responsible for each of the seven recorded cholera pandemics.
Stephen A. Berger, Itzhak Shapiro
openaire   +3 more sources

A dysbiotic gut microbiome suppresses antibody mediated-protection against Vibrio cholerae

open access: yesiScience, 2021
Summary: Cholera is a severe diarrheal disease that places a significant burden on global health. Cholera’s high morbidity demands effective prophylactic strategies, but oral cholera vaccines exhibit variable efficacy in human populations.
John C. Macbeth   +3 more
doaj   +1 more source

Vaccination strategies to combat an infectious globe: Oral cholera vaccines

open access: yesJournal of Global Infectious Diseases, 2011
Cholera is a substantial health burden in many countries in Africa and Asia, where it is endemic. It is as well responsible for ongoing epidemics in sub-Saharan Africa which are becoming greater in terms of frequency, extension, and duration.
Rosa M López-Gigosos   +3 more
doaj   +1 more source

Stockpiling oral cholera vaccine

open access: yesBulletin of the World Health Organization, 2012
Cholera is re-emerging as a threat on the global public health stage. The number of reported cases worldwide is back at the peak level observed two decades ago,1 new Vibrio cholerae strains have appeared and antimicrobial resistance has increased. Weak surveillance systems and the possibility of travel and trade sanctions contribute to widespread ...
William Perea   +2 more
openaire   +4 more sources

Methods to assess the impact of mass oral cholera vaccination campaigns under real field conditions. [PDF]

open access: yesPLoS ONE, 2014
There is increasing interest to use oral cholera vaccination as an additional strategy to water and sanitation interventions against endemic and epidemic cholera.
Jacqueline Deen   +2 more
doaj   +1 more source

Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae

open access: yesmSphere, 2019
Vibrio cholerae infection provides long-lasting protective immunity, while oral, inactivated cholera vaccines (OCV) result in more-limited protection. To identify characteristics of the innate immune response that may distinguish natural V.
Ana A. Weil   +13 more
doaj   +1 more source

Oral Vaccines Against Cholera [PDF]

open access: yesClinical Infectious Diseases, 2011
The current seventh pandemic of cholera, caused by serogroup O1, El Tor biotype, has now involved almost the entire developing world. The ongoing dynamic epidemiology of cholera, involving evolution of new strains, prolonged and more frequent epidemics, increased antimicrobial resistance, and awareness of the role of climate change upon the global ...
John D. Clemens   +3 more
openaire   +3 more sources

Cholera: An Overview with Reference to the Syrian Outbreak

open access: yesAvicenna Journal of Medicine, 2023
Cholera is an acute type of diarrheal disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. The disease is still endemic in almost 69 countries, accounting for around 2.86 million cases and 95,000 deaths annually ...
Munawar Hraib   +6 more
doaj   +1 more source

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