Results 21 to 30 of about 15,696 (168)
Efficacy and Safety of Cholera Vaccines
Биопрепараты: Профилактика, диагностика, лечение, 2018 Cholera is an acute diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and O139 serogroups. It still remains a major global healthcare problem.
A. A. Goryaev +3 more
doaj +1 more source
Water, Hygiene and Inequality: Keys to Understanding and Combating the Current Cholera Epidemic in the Democratic Republic of Congo-A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aim The Democratic Republic of the Congo (DRC) is among the countries most affected by cholera in the world. Since the 1970s, endemic foci have persisted in the eastern lake provinces, where chronic armed conflict, massive population displacement, and extreme socioeconomic inequalities create particularly favorable conditions ...
Yokolo H +4 more
europepmc +2 more sources
Cholera Specific Prophylaxis in Modern Conditions
Проблемы особо опасных инфекций, 2011 Described is cholera epidemiological situation in the world and in the Russian Federation. One of the causes of its deterioration is pointed out to be the emergence, in the modern period, of altered Vibrio cholerae eltor variants with increased virulence,
G. G. Onishchenko +6 more
doaj +1 more source
Stemming cholera tides in Zimbabwe through mass vaccination
International Journal of Infectious Diseases, 2020 Background: In 2018, Zimbabwe declared another major cholera outbreak a decade after recording one of the worst cholera outbreaks in Africa. Methods: A mathematical model for cholera was used to estimate the magnitude of the cholera outbreak and ...
Zindoga Mukandavire +5 more
doaj +1 more source
mBio, 2022 Human challenge studies are instrumental for testing cholera vaccines, but these studies use outdated strains and require inpatient facilities. Here, we created next-generation isogenic Ogawa and Inaba O1 V.
Bolutife Fakoya +6 more
doaj +1 more source
Vaccines in the time of cholera [PDF]
Proceedings of the National Academy of Sciences, 2011 Cholera, an acute watery diarrheal disease caused by Vibrio cholerae 01 and, less commonly, by V. cholerae 0139, is a major global public health problem in developing countries, causing an estimated 100,000 deaths per year and resulting in major microeconomic and macroeconomic losses.
openaire +2 more sources
IMPROVEMENT OF SPECIFIC CHOLERA PREVENTION USING IMMUNOMODULATORS
Медицинская иммунология, 2021 It is known that the combined use of vaccines, cytokines and various immunomodulatory drugs contributes to the development of a full-fledged immune response.
A. V. Filippenko +4 more
doaj +1 more source
Intradermal cholera vaccination [PDF]
Journal of Hygiene, 1964 The protection afforded by cholera vaccine administered by the intradermal route, and demonstrated by active and passive mouse protection tests, active guinea-pig protection tests, and agglutination titres, is excellent and equal to that given by subcutaneous inoculation.It is suggested that cholera vaccine administered by the intradermal route would ...
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Combating Cholera [version 1; peer review: 2 approved]
F1000Research, 2019 Cholera infections caused by the gamma-proteobacterium Vibrio cholerae have ravaged human populations for centuries, and cholera pandemics have afflicted every corner of the globe.
Brian Y. Hsueh, Christopher M. Waters
doaj +1 more source
Production of putative enhanced oral cholera vaccine strains that express toxin-coregulated pilus. [PDF]
PLoS ONE, 2017 The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V.
Caitlyn A Hauke, Ronald K Taylor
doaj +1 more source