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An Update on Cholera Immunity and Current and Future Cholera Vaccines [PDF]

open access: yesTropical Medicine and Infectious Disease, 2021
Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or vaccination.
Jan Holmgren
doaj   +2 more sources

Cholera, the Current Status of Cholera Vaccines and Recommendations for Travellers [PDF]

open access: yesVaccines, 2020
Cholera is endemic in approximately 50 countries, primarily in Africa and South and Southeast Asia, and in these areas, it remains a disease associated with poverty.
Giovanni Gabutti   +8 more
doaj   +2 more sources

Oral cholera vaccines and their impact on the global burden of disease [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2019
With one-third of nations at risk of cholera, we can expect to experience massive, rapidly disseminated, and prolonged cholera outbreaks such as those recently experienced in Yemen and Haiti.
Thomas F. Wierzba
doaj   +2 more sources

Allocation of Oral Cholera Vaccines in Africa [PDF]

open access: yesVaccines
Objectives: In this study, we examine the allocation of oral cholera vaccines (OCVs) across 25 African countries between 2013 and 2019. Methods: We constructed a dataset combining cholera outbreaks and requests, decisions, and deliveries of OCVs from the
Elisa M. Maffioli, Yutong Lu
doaj   +2 more sources

Prospective observational studies to provide confidence in the protection conferred by newer generation, inactivated oral cholera vaccines: a proposal [PDF]

open access: yesEClinicalMedicine
Summary: Inactivated oral cholera vaccines (OCVs) are a cornerstone of international efforts to control cholera, and are currently deployed from a global stockpile for the control of epidemics and endemic hotspots, as well as for humanitarian emergencies.
John Clemens   +2 more
doaj   +2 more sources

Achievements and challenges for the use of killed oral cholera vaccines in the global stockpile era [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Cholera remains an important but neglected public health threat, affecting the health of the poorest populations and imposing substantial costs on public health systems.
Sachin N. Desai   +6 more
doaj   +2 more sources

Oral killed cholera vaccines for preventing cholera. [PDF]

open access: yesCochrane Database Syst Rev
Cholera causes acute watery diarrhoea and death if not properly treated. Outbreaks occur in areas with poor sanitation, including refugee camps. Several vaccines have been developed and tested over the last 50 years. This is an update of a Cochrane review, originally published in 1998, which explored the effects of all vaccines for preventing cholera ...
Saif-Ur-Rahman KM   +4 more
europepmc   +3 more sources

An overview of VaxchoraTM, a live attenuated oral cholera vaccine [PDF]

open access: bronzeHuman Vaccines & Immunotherapeutics, 2020
Cholera remains a public health threat among the least privileged populations and regions affected by conflicts and natural disasters. Together with Water, Sanitation and Hygiene practices, use of oral cholera vaccines (OCVs) is a key tool to prevent ...
Tarun Saluja   +4 more
doaj   +2 more sources

Uptake likelihood assessment of oral cholera vaccine capsules: insights from stakeholder consultations in five countries [PDF]

open access: yesBMC Public Health
Background The global resurgence of cholera, a diarrhoeal disease, has resulted in vaccine demand that exceeds the currently available supply resulting in global calls for next generation cholera vaccines.
Dijana Spasenoska   +6 more
doaj   +2 more sources

Controlling cholera in the Ouest Department of Haiti using oral vaccines.

open access: goldPLoS Neglected Tropical Diseases, 2017
Following the 2010 cholera outbreak in Haiti, a plan was initiated to provide massive improvements to the sanitation and drinking water infrastructure in order to eliminate cholera from the island of Hispaniola by 2023.
Alexander Kirpich   +4 more
doaj   +3 more sources

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