Cholera, the Current Status of Cholera Vaccines and Recommendations for Travellers [PDF]
Vaccines, 2020 Cholera is endemic in approximately 50 countries, primarily in Africa and South and Southeast Asia, and in these areas, it remains a disease associated with poverty.
Armando Stefanati +2 more
exaly +4 more sources
Oral killed cholera vaccines for preventing cholera [PDF]
The Cochrane LibraryCholera causes acute watery diarrhoea and death if not properly treated. Outbreaks occur in areas with poor sanitation, including refugee camps. Several vaccines have been developed and tested over the last 50 years. This is an update of a Cochrane review, originally published in 1998, which explored the effects of all vaccines for preventing cholera ...
James Meiring
exaly +7 more sources
An Update on Cholera Immunity and Current and Future Cholera Vaccines [PDF]
Tropical Medicine and Infectious Disease, 2021 Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or vaccination.
Jan Holmgren
doaj +2 more sources
Controlling Endemic Cholera with Oral Vaccines [PDF]
PLoS Medicine, 2007 Although advances in rehydration therapy have made cholera a treatable disease with low case-fatality in settings with appropriate medical care, cholera continues to impose considerable mortality in the world's most impoverished populations ...
Ira Longini +2 more
exaly +2 more sources
Oral cholera vaccines and their impact on the global burden of disease [PDF]
Human Vaccines & Immunotherapeutics, 2019 With one-third of nations at risk of cholera, we can expect to experience massive, rapidly disseminated, and prolonged cholera outbreaks such as those recently experienced in Yemen and Haiti.
Thomas F. Wierzba
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Allocation of Oral Cholera Vaccines in Africa [PDF]
VaccinesObjectives: In this study, we examine the allocation of oral cholera vaccines (OCVs) across 25 African countries between 2013 and 2019. Methods: We constructed a dataset combining cholera outbreaks and requests, decisions, and deliveries of OCVs from the
Elisa M. Maffioli, Yutong Lu
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Prospective observational studies to provide confidence in the protection conferred by newer generation, inactivated oral cholera vaccines: a proposal [PDF]
EClinicalMedicineSummary: Inactivated oral cholera vaccines (OCVs) are a cornerstone of international efforts to control cholera, and are currently deployed from a global stockpile for the control of epidemics and endemic hotspots, as well as for humanitarian emergencies.
John Clemens +2 more
doaj +2 more sources
Achievements and challenges for the use of killed oral cholera vaccines in the global stockpile era [PDF]
Human Vaccines & Immunotherapeutics, 2017 Cholera remains an important but neglected public health threat, affecting the health of the poorest populations and imposing substantial costs on public health systems.
Sachin N. Desai +6 more
doaj +2 more sources
The case for evaluation of double mutant heat-labile toxin as an adjuvant to improve oral cholera vaccine immunogenicity [PDF]
Frontiers in ImmunologyCholera has re-emerged as a major global public health threat. Orally administered attenuated or inactivated vaccines offer protection against enteric pathogens such as Vibrio cholerae, and several World Health Organization-prequalified oral cholera ...
A. Louis Bourgeois +8 more
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Vibrio cholerae O1 classical and El Tor toxin-coregulated pilus subunit A (TcpA) epitopes that induce biotype-specific and cross-protective antibodies against bacterial adherence [PDF]
Applied and Environmental MicrobiologyThe persistent and deadly cholera remains a significant burden on global health. Current countermeasures are inadequate against cholera. Toxin-coregulated pilin (TCP) has long been a target for understanding the biogenesis of Vibrio cholerae infection ...
Sai Simha Reddy Vakamalla +2 more
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