Results 31 to 40 of about 15,696 (168)

The influence of immunomodulators on the formation of vaccine-induced cholera immunity

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2022
Introduction. Due to the remaining tense situation on cholera in the world, research continues on the creation of new preventive drugs, as well as ways to increase the immunogenicity of existing anti-cholera vaccines.
A. V. Filippenko   +3 more
doaj   +1 more source

A dysbiotic gut microbiome suppresses antibody mediated-protection against Vibrio cholerae

open access: yesiScience, 2021
Summary: Cholera is a severe diarrheal disease that places a significant burden on global health. Cholera’s high morbidity demands effective prophylactic strategies, but oral cholera vaccines exhibit variable efficacy in human populations.
John C. Macbeth   +3 more
doaj   +1 more source

Methods to assess the impact of mass oral cholera vaccination campaigns under real field conditions. [PDF]

open access: yesPLoS ONE, 2014
There is increasing interest to use oral cholera vaccination as an additional strategy to water and sanitation interventions against endemic and epidemic cholera.
Jacqueline Deen   +2 more
doaj   +1 more source

Russian vaccines against especially dangerous bacterial pathogens

open access: yesEmerging Microbes and Infections, 2014
In response to the epidemiological situation, live attenuated or killed vaccines against anthrax, brucellosis, cholera, glanders, plague and tularemia were developed and used for immunization of at-risk populations in the Former Soviet Union.
Valentina A Feodorova   +3 more
doaj   +1 more source

Vaccination strategies to combat an infectious globe: Oral cholera vaccines

open access: yesJournal of Global Infectious Diseases, 2011
Cholera is a substantial health burden in many countries in Africa and Asia, where it is endemic. It is as well responsible for ongoing epidemics in sub-Saharan Africa which are becoming greater in terms of frequency, extension, and duration.
Rosa M López-Gigosos   +3 more
doaj   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

open access: yesAdvanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira   +7 more
wiley   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

open access: yesAnimal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali   +10 more
wiley   +1 more source

Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae

open access: yesmSphere, 2019
Vibrio cholerae infection provides long-lasting protective immunity, while oral, inactivated cholera vaccines (OCV) result in more-limited protection. To identify characteristics of the innate immune response that may distinguish natural V.
Ana A. Weil   +13 more
doaj   +1 more source

Cholera: An Overview with Reference to the Syrian Outbreak

open access: yesAvicenna Journal of Medicine, 2023
Cholera is an acute type of diarrheal disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. The disease is still endemic in almost 69 countries, accounting for around 2.86 million cases and 95,000 deaths annually ...
Munawar Hraib   +6 more
doaj   +1 more source

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse   +4 more
wiley   +1 more source

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