Results 291 to 300 of about 76,819 (327)
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Seminars in Dermatology, 1995
The pruritus of cholestasis is a difficult clinical problem to manage. The pathogenesis of this symptom is unknown. All conventional therapies have been unsuccessful in isolating a particular group of substances that could be implicated as direct or indirect causative agents.
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The pruritus of cholestasis is a difficult clinical problem to manage. The pathogenesis of this symptom is unknown. All conventional therapies have been unsuccessful in isolating a particular group of substances that could be implicated as direct or indirect causative agents.
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Seminars in Liver Disease, 2004
Hepatic formation of bile is critical to survival and is one of the most easily disrupted liver functions. Liver biopsy is performed to obtain a definitive diagnosis of cause, to exclude potential etiologies, or simply to assist in development of a differential diagnosis. Parenchymal changes of cholestasis (feathery degeneration of hepatocytes, dilated
James M. Crawford, Melissa K. Li
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Hepatic formation of bile is critical to survival and is one of the most easily disrupted liver functions. Liver biopsy is performed to obtain a definitive diagnosis of cause, to exclude potential etiologies, or simply to assist in development of a differential diagnosis. Parenchymal changes of cholestasis (feathery degeneration of hepatocytes, dilated
James M. Crawford, Melissa K. Li
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The Pathogenesis of Cholestasis
Hospital Practice, 1990How does cholestasis develop when there is no obvious obstruction, destruction, or malformation of bile ducts? Recent findings on bile formation and flow are reviewed, and two models of intrahepatic cholestasis are presented: one of rapid onset, which is bile acid induced, and the other of slow onset, which is estrogen induced.
Roger Lester, P Zimniak, Anna Radominska
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Intrahepatic Cholestasis of Pregnancy
Clinical obstetrics and gynecology, 2019Intrahepatic cholestasis of pregnancy is a common disorder of pregnancy manifested by pruritus and elevated bile acids. The etiology of cholestasis is poorly understood and management is difficult due to the paucity of data regarding its diagnosis ...
Devin D. Smith, Kara M. Rood
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Pediatric Annals, 2016
Jaundice is a key manifestation of hepatobiliary disease in all age groups. Jaundice is a common finding in the first 2 weeks after birth, occurring in 2.4% to 15% of newborns. The neonatal liver is at increased susceptibility to cholestasis, with an incidence ranging from 1 in 2,500 to 1 in 5,000 live births. Etiologies vary, but the most
Melissa G Andrianov, Ruba Azzam
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Jaundice is a key manifestation of hepatobiliary disease in all age groups. Jaundice is a common finding in the first 2 weeks after birth, occurring in 2.4% to 15% of newborns. The neonatal liver is at increased susceptibility to cholestasis, with an incidence ranging from 1 in 2,500 to 1 in 5,000 live births. Etiologies vary, but the most
Melissa G Andrianov, Ruba Azzam
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Obstetrics and Gynecology Clinics of North America, 2010
Intrahepatic cholestasis (ICP) of pregnancy is a disease that is likely multifactorial in etiology and has a prevalence that varies by geography and ethnicity. The diagnosis is made when patients have a combination of pruritus and abnormal liver-function tests.
Lili Sheibani +2 more
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Intrahepatic cholestasis (ICP) of pregnancy is a disease that is likely multifactorial in etiology and has a prevalence that varies by geography and ethnicity. The diagnosis is made when patients have a combination of pruritus and abnormal liver-function tests.
Lili Sheibani +2 more
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Hyperbilirubinemia and cholestasis
The American Journal of Medicine, 1978Although the morphologist continues to describe cholestasis on the basis of precipitated bile seen on light microscopic sections of the liver or dilated canaliculi with loss of microvilli seen by electron microscopy, the physiologist can distinguish clearly between hyperbilirubinemia and cholestasis.
Norman B. Javitt, Paul D. Berk
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Fetal and Maternal Medicine Review, 2004
Obstetric cholestasis (OC) is defined as pruritus of onset in pregnancy in association with abnormal liver function in the absence of any other identifiable liver pathology which resolves on delivery. It may be associated with adverse obstetric outcome and significant maternal morbidity.
Kenyon, A P, Shennan, A
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Obstetric cholestasis (OC) is defined as pruritus of onset in pregnancy in association with abnormal liver function in the absence of any other identifiable liver pathology which resolves on delivery. It may be associated with adverse obstetric outcome and significant maternal morbidity.
Kenyon, A P, Shennan, A
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Pediatrics in Review, 2004
Any infant who is jaundiced beyond two to three weeks of life should be evaluated for neonatal cholestasis. Neonatal cholestasis is defined as accumulation of bile substances in blood due to impaired excretion. These infants should always have fractionated serum bilirubin levels checked to differentiate the conjugated hyperbilirubinemia of cholestasis ...
Sridevi, Venigalla, Glenn R, Gourley
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Any infant who is jaundiced beyond two to three weeks of life should be evaluated for neonatal cholestasis. Neonatal cholestasis is defined as accumulation of bile substances in blood due to impaired excretion. These infants should always have fractionated serum bilirubin levels checked to differentiate the conjugated hyperbilirubinemia of cholestasis ...
Sridevi, Venigalla, Glenn R, Gourley
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Medicine, 2002
Cholestasis (impairment of, or reduction in, bile flow) can both pre-dispose to the development of chronic liver disease and result in its own specific symptoms. The severity of cholestatic symptoms (which can often dramatically impinge on quality of life in their own right) is typically independent of the severity of the underlying liver disease, the ...
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Cholestasis (impairment of, or reduction in, bile flow) can both pre-dispose to the development of chronic liver disease and result in its own specific symptoms. The severity of cholestatic symptoms (which can often dramatically impinge on quality of life in their own right) is typically independent of the severity of the underlying liver disease, the ...
openaire +2 more sources