Results 31 to 40 of about 75,500 (262)

Histopathological diagnosis of intra- and extrahepatic neonatal cholestasis

Brazilian Journal of Medical and Biological Research, 1998
The histopathology of the liver is fundamental for the differential diagnosis between intra- and extrahepatic causes of neonatal cholestasis. However, histopathological findings may overlap and there is disagreement among authors concerning those which ...
J.L. Santos, H. Almeida, C.T.S. Cerski, T.R. Silveira   +3 more
doaj   +1 more source

A meta-analysis of the prevalence of gestational diabetes in patients diagnosed with obstetrical cholestasisAJOG Global Reports at a Glance

AJOG Global Reports, 2021
BACKGROUND: Gestational diabetes and obstetrical cholestasis are common clinical conditions seen in clinical practice. There is evidence suggesting a coexisting relationship that could have a potential clinical implication related to stillbirth outcomes.
Manoj Mohan, MRCOG, Sanjay Swargathmadhom Prabhu, MRCOG, Abdul Kareem Pullattayil, MSIt, Stephen Lindow, FRCOG   +3 more
doaj  

Changes in activity of metalloproteinases 2 and 9 in rat liver in experimental model of cholestasis taking into account its duration and assessment of selected features

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: Cholestasis, otherwise known as bile stasis, occurs when the flow of bile is blocked. There are currently two types of cholestasis: extrahepatic and intrahepatic.
Krzysztof Suszyński, Natalia Białoń, Dariusz Górka, Anna Dolińska, Mikołaj Górka   +4 more
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

Cells, 2020
Hydrophobic bile salts are considered to promote liver fibrosis in cholestasis. However, evidence for this widely accepted hypothesis remains scarce. In established animal models of cholestasis, e.g., by Mdr2 knockout, cholestasis and fibrosis are both ...
S. Hohenester, V. Kanitz, A. Kremer, C. Paulusma, Ralf Wimmer, Helen Kuehn, G. Denk, D. Horst, R. O. Oude Elferink, U. Beuers   +9 more
semanticscholar   +1 more source

DIFFERENCES OF BIRTH WEIGHT AND ONSET OF ACHOLIC STOOL BETWEEN EXTRAHEPATIC AND INTRAHEPATIC CHOLESTASIS

Indonesian Midwifery and Health Sciences Journal
Background: Biliary atresia (extrahepatic cholestasis) and neonatal hepatitis (intrahepatic cholestasis) are two main causes of cholestasis. It is important to distinguish the type of cholestasis for determine management.
Bagus Setyoboedi, Lasmauli Situmorang, Rendi Aji Prihaningtyas, Sjamsul Arief   +3 more
doaj   +1 more source

Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

Gynecology Obstetrics & Reproductive Medicine, 2021
OBJECTIVES: We aimed to determine whether mean platelet volume value and/or neutrophil/lymphocyte ratio values are useful as a predictive marker for gestational cholestasis.
Hasan Eroglu, Harun Egemen Tolunay, Kemal Sarsmaz, Gokcen Orgul, Dilek Sahin, Aykan Yucel   +5 more
doaj   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Exploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong, Xin Han, Qiao Yang, Roufen Chen, Liteng Shen, Lei Xu, Lu Wang, Bo Zhu, Dongxin Tang, Shuosheng Zhang, Keda Lu, Mengyun Peng, Gang Cao   +15 more
wiley   +1 more source

Quality Measures to Enhance the Management and Treatment of Primary Biliary Cholangitis: A Delphi Consensus Study. [PDF]

Liver Int
ABSTRACT Background & Aims Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterised by bile duct destruction, leading to cholestasis and fibrosis. Despite therapeutic advancements, gaps remain in diagnostic standardisation, treatment response evaluation, and patient‐centred care. This study aimed to develop consensus‐driven
Alvaro D, Calvaruso V, Carbone M, Cazzagon N, Floreani A, Invernizzi P, Marzioni M, Pasqualetti P, Pennisi G, Toniutto P, Vespasiani-Gentilucci U, Craxì A.   +11 more
europepmc   +2 more sources