Results 41 to 50 of about 116,093 (277)

Compound Heterozygous MYO5B Mutation, a Cause of Infantile Cholestasis: A Case Report

Journal of Nepal Medical Association, 2022
Infantile cholestasis is a common clinical problem in early infancy characterised by impairment in bile formation and/or flow. It requires prompt evaluation for underlying aetiology to initiate appropriate management.
Muna Khanal, Adarsh Kumar Jha, Arun Kumar Sharma   +2 more
doaj   +1 more source

Transcriptional and Post-Transcriptional Anticholestatic Mechanisms of Obeticholic Acid in Lipopolysaccharide-Induced Cholestasis. [PDF]

Pharmaceutics
Razori MV, Hillotte GL, Martín PL, Barosso IR, Basiglio CL, Ruiz ML, Roma MG.   +6 more
europepmc   +3 more sources

Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in earlyand late-stage cholestasis [PDF]

, 2017
AIM: To ascertain whether cholestasis affects the expression of two CYP3A isoforms (CYP3A1 and CYP3A2) and of pregnane X receptor (PXR) and constitutive androstane receptor (CAR).
Albertoni, Laura, Baldo, Vincenzo, Baldovin, Tatjana, Carrara, Maria, DALLA POZZA, Arianna, De Martin, Sara, Floreani, Annarosa, Gabbia, Daniela, Lazzari, Roberta, Zigiotto, Giorgia   +9 more
core   +1 more source

Recreational exposure during algal bloom in carrasco beach, uruguay: A liver failure case report [PDF]

, 2017
In January 2015, a 20-month-old child and her family took part in recreational activities at Carrasco and Malvín beaches (Montevideo, Uruguay). An intense harmful algae bloom (HAB) was developing along the coast at that time.
Andrinolo, Dario, Caixach, Josep, Cavalieri, María Lorena, D'Agostino, Daniel, Flores, Cintia, Mullen, Eduardo, Parot Varela, María Macarena, Sedan, Daniela Yazmine, Vidal, Flavia   +8 more
core   +3 more sources

Molecular overview of progressive familial intrahepatic cholestasis

World Journal of Gastroenterology, 2020
Cholestasis is a clinical condition resulting from the imapairment of bile flow. This condition could be caused by defects of the hepatocytes, which are responsible for the complex process of bile formation and secretion, and/or caused by defects in the ...
Sriram Amirneni, Nils Haep, M. A. Gad, A. Soto‐Gutierrez, J. Squires, R. Florentino   +5 more
semanticscholar   +1 more source

Benign recurrent intrahepatic cholestasis

Definitions, 2020
Benign recurrent intrahepatic cholestasis (BRIC) is characterized by episodes of liver dysfunction called cholestasis. During these episodes, the liver cells have a reduced ability to release a digestive fluid called bile.
Alexander K. C. Leung, M. Schmitt, Christie P. Thomas, Cord Sunderkötter, M. Schiller, Thomas Schwarz, M. Berneburg, A. Kohlschütter, Lorenzo Cerroni, H. Direşkeneli, Kenneth Calamia, Gloria L. David, D. Zeldin, B. Schütte, Lee A. Denson, Andreas Erhardt, Ralf Kubitz, D. Häussinger, W. Sealey, Donald M. Mock, Barry Wolf, Johannes Schumacher, P. Propping, D. Metze, Andrew L. Wong, M. Hengstschläger, Whitney A. High, Kenneth R Shroyer, M. E. Mccready, Dennis E. Bulman, Ali R. Afzal, David B. Everman, C. Stoll, S. Darcan, Y. Kou, You Shuei Lin, Yoichi Suzuki, Keiya Tada, S. Kupka, Wolfgang Dietmaier, Arndt Hartmann, R. Hennekam, J. Belperio, Michael P. Keane, M. Iain Smith, Robert M. Strieter, Nestor A. Molfino, F. Sciandra, T. Rossenbacker, S. Priori, Marco Senzolo, C. Triantos, Dimitrios Samonakis, E. Cholongitas, A. Burroughs, Marco Mura, Markus Braun-Falco, S. Hofmann, Leena Bruckner‐Tuderman   +58 more
semanticscholar   +1 more source

EVALUATION OF RISK FACTORS FOR INTRAHEPATIC CHOLESTASIS OF PREGNANCY IN PATIENTS PRESENTING TO A TERTIARY CARE CENTRE

Pakistan Armed Forces Medical Journal, 2021
Objectives: To evaluate the principal risk factors associated with development of intrahepatic cholestasis of pregnancy (ICP) in patients presenting to a tertiary care hospital. Study Design: Case control study.
Rabiah Anwar, Kashif Razzaq, Aysha Shahid, Afeera Afsheen, Amera Tariq, Irum Saleem   +5 more
doaj  

Histopathological diagnosis of intra- and extrahepatic neonatal cholestasis

Brazilian Journal of Medical and Biological Research, 1998
The histopathology of the liver is fundamental for the differential diagnosis between intra- and extrahepatic causes of neonatal cholestasis. However, histopathological findings may overlap and there is disagreement among authors concerning those which ...
J.L. Santos, H. Almeida, C.T.S. Cerski, T.R. Silveira   +3 more
doaj   +1 more source

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]

, 2019
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George, Bacon, Bruce, Bowlus, Christopher L, Dorenbaum, Alejandro, Gu, Joan, Hirschfield, Gideon M, Jones, David, Kennedy, Ciara, Levy, Cynthia, Luketic, Velimir, Mayo, Marlyn J, Medendorp, Sharon, Novak, Patricia, Patanwala, Imran, Pockros, Paul J, Vuppalanchi, Raj   +15 more
core   +2 more sources

Changes in activity of metalloproteinases 2 and 9 in rat liver in experimental model of cholestasis taking into account its duration and assessment of selected features

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: Cholestasis, otherwise known as bile stasis, occurs when the flow of bile is blocked. There are currently two types of cholestasis: extrahepatic and intrahepatic.
Krzysztof Suszyński, Natalia Białoń, Dariusz Górka, Anna Dolińska, Mikołaj Górka   +4 more
doaj   +1 more source