Results 11 to 20 of about 55,634 (225)

An in-depth discussion of cholesteatoma, middle ear Inflammation, and langerhans cell histiocytosis of the temporal bone, based on diagnostic results. [PDF]

Front Pediatr, 2022
Objective This study aimed to conduct an in-depth investigation of the learning framework used for deriving diagnostic results of temporal bone diseases, including cholesteatoma and Langerhans cell histiocytosis (LCH).
Duan B, Pan LL, Chen WX, Qiao ZW, Xu ZM.
europepmc   +2 more sources

Adult Case of Congenital Intratympanic Membrane Cholesteatoma. [PDF]

Clin Case Rep
ABSTRACT Intratympanic membrane cholesteatoma (ITMC) is a rare type of cholesteatoma located within the tympanic membrane. Surgery is a treatment option if the ITMCs do not spontaneously disappear. Transcanal endoscopic ear surgery is anticipated to become the standard approach in the future.
Fukui J, Fukumoto I, Koshizuka K, Iinuma T, Yamasaki K, Yonekura S, Nemoto T, Hanazawa T.   +7 more
europepmc   +2 more sources

Endoscopic ear surgery in middle ear cholesteatoma

Laparoscopic, Endoscopic and Robotic Surgery, 2021
Objective: Endoscope has been used as diagnostic tool for recidivism and as an adjunct to microscopic technique in the management of cholesteatoma. At present transcanal endoscopic ear surgery (TEES) is being used as a minimally invasive alternative for ...
Satish Nair, J.G. Aishwarya, Nagamani Warrier, V Pavithra, Aditya Jain, Mehrin Shamim, Krishna Ramanathan, Pooja K. Vasu   +7 more
doaj   +3 more sources

Identification of Differential Metabolites in Chronic Suppurative Otitis Media With Non-Targeted and Targeted Metabolomics Approach. [PDF]

Smart Med
Untargeted metabolomics is used to analyze tissue samples from chronic suppurative otitis media patients with or without cholesteatoma and identify metabolic differences across groups stratified by CT scores. Targeted metabolomic validation in an independent cohort verified five candidate metabolites. ABSTRACT Chronic suppurative otitis media (CSOM) is
Hu L, Zhu Y, Wu C, Liu X, Wang Q, Huang Y, Liu H, Chen X, Wu W, Jiang H.   +9 more
europepmc   +2 more sources

The value of otoendoscopy in the management of middle ear cholesteatoma

Journal of Research in Medical Sciences, 2015
Background: The surgical management of cholesteatoma is a controversial issue, particularly regarding intact-canal-wall mastoidectomy (ICWM) versus canal-wall-down mastoidectomy (CWDM).
Sayed Hamidreza Abtahi, Farzaneh Abootalebian, Mehrdad Rogha, Nezamoddin Berjis   +3 more
doaj   +4 more sources

Temporal Bone Carcinoma Masquerading as Complicated Chronic Otitis Media. [PDF]

Clin Case Rep
ABSTRACT This case highlights the importance of early recognition of chronic ear discharge, facial nerve palsy, and swelling as potential indicators of aggressive conditions like squamous cell carcinoma. Future research should focus on improving early diagnostic techniques and ensuring continuity of care in advanced malignancies.
Shrestha SR, Malhotra M, Bhardwaj A, Suji PS, Khan SA.   +4 more
europepmc   +2 more sources

Expression of tumor necrosis factor alpha, interleukin-1 and matrix metalloproteinase-9 and pathomorphological changes in acquired middle ear cholesteatoma [PDF]

Biomedicinska istraživanja, 2021
Introduction. The inflammatory mediators play a central role in the pathogenesis of the inflammatory process of the middle ear and cholesteatoma from the aspect of initiating and maintaining the inflammatory response to infection and lesion.
Dalibor Vranješ, Predrag Špirić, Mirjana Gnjatić   +2 more
doaj   +1 more source

Bacteriome of the Middle Ear in Children and Young Adults With Cholesteatoma and Retraction Pocket: A Pilot Study [PDF]

OTO Open
Objective Chronic otitis media (COM) is a common middle ear disease in children and young adults. Dysfunction of the Eustachian tube and bacterial infection are the main causes. This pilot study aimed to describe and compare bacteriomes of the middle ear
Michal Bartos, Milan Urik, Lucie Buresova, Pavla Holochova, Eva Budinska, Petra Borilova Linhartova   +5 more
doaj   +2 more sources

Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma

Frontiers in Genetics, 2023
Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie, Li Jin, Jun He, Jinfeng Fu, Tuanfang Yin, Jihao Ren, Wei Liu   +6 more
doaj   +1 more source

Review of potential medical treatments for middle ear cholesteatoma

Cell Communication and Signaling, 2022
Middle ear cholesteatoma (MEC), is a destructive, and locally invasive lesion in the middle ear driven by inflammation with an annual incidence of 10 per 100,000.
M. Schürmann, P. Goon, H. Sudhoff
semanticscholar   +1 more source