Increased Risk of Cholesteatoma in Individuals With Alpha-1 Antitrypsin Deficiency: A Cohort Study. [PDF]
Patients with AATD had a 3.6‐fold increased risk of cholesteatoma surgery (HR: 3.62) compared to controls. These findings suggest that AATD may contribute to the development of cholesteatoma. ABSTRACT Objective To estimate the risk of cholesteatoma in patients with alpha‐1 antitrypsin deficiency (AATD) compared to the general population using time‐to ...
Ali A, Ravn HA, Dahl M, Djurhuus BD.
europepmc +2 more sources
The Global Burden of Cholesteatoma: A Systematic Review and Meta-analysis. [PDF]
Abstract Objective This systematic review and meta‐analysis sought to estimate the global and World Health Organization (WHO) regional prevalence and burden of cholesteatoma. Data Sources PubMed, APA PsycINFO, the Cochrane Library, Embase, and WHO International Clinical Trials Registry Platform (ICTRP) from 2010 to 2025.
Melariri H +21 more
europepmc +2 more sources
The significance of the expression of cell proliferation and inflammation markers in the development of acquired middle ear cholesteatoma [PDF]
Background/Aim. Permanent proliferation and periodical infection are the main clinical characteristics of acquired middle ear cholesteatoma. The aim of this study was to research immunohistochemical characteristics of the skin along with the ...
Erdoglija Milan +5 more
doaj +1 more source
The middle ear is a small and hard to reach compartment, limiting the amount of tissue that can be extracted and the possibilities for studying the molecular mechanisms behind diseases like cholesteatoma.
Cecilia Drakskog +6 more
doaj +2 more sources
Transcanal Endoscopic Ear Surgery for Congenital Cholesteatoma [PDF]
Objectives As endoscopic instrumentation, techniques and knowledges have significantly improved recently, endoscopic ear surgery has become increasingly popular. Transcanal endoscopic ear surgery (TEES) can provide better visualization of hidden areas in
Joo Hyun Park, Jungmin Ahn, Il Joon Moon
doaj +1 more source
Middle ear cholesteatoma in two cats diagnosed with the aid of video-otoscopy
Case series summary The present report describes middle ear cholesteatoma in two cats and also the use of video-otoscopy and flushing to assist with the diagnosis.
Cristiane Bazaga Botelho +5 more
doaj +1 more source
A fluorescent photoimmunoconjugate for imaging of cholesteatoma
Cholesteatoma is a potentially serious complication of chronic ear infections and requires surgical intervention for definitive management. Long-term complications include a frequent need for repeat surgical intervention for disease recurrence, and ...
Samuel Early +6 more
doaj +1 more source
Radical surgery on the middle ear in the treatment of cholesteatoma: history or reality? A review
Radical surgery on the middle ear is primarily associated with such pathology as cholesteatoma and ear neoplasms. And if in the case of tumors radicalism in ear surgery is justified, then in the surgery of the cholesteatomic process there is a need to ...
Vadim S. Isachenko +4 more
doaj +1 more source
Cholesteatoma and family history: An international survey [PDF]
Objective To explore the relative frequency of a family history of cholesteatoma in patients with known cholesteatoma, and whether bilateral disease or earlier diagnosis is more likely in those with a family history.
Clark, Allan +6 more
core +1 more source
Are Hounsfield Unit Measurements of Bony Absorption Changes in Cholesteatoma Helpful?
Introduction High-resolution computed tomography (HRCT) scans of the temporal bone are used to assess the bony erosion of the middle-ear structures whenever cholesteatoma is suspected. Objective To study the differences in HRCT Hounsfield unit
Shay Shemesh +4 more
doaj +1 more source

