Results 21 to 30 of about 55,634 (225)

Microarray analysis and functional prediction of differentially expressed circular RNAs in acquired middle ear cholesteatoma

open access: yesBioMedical Engineering OnLine, 2021
Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie   +4 more
doaj   +1 more source

Classification and Stages of Middle Ear Cholesteatoma at the Southern Philippines Medical Center Using the European Academy of Otology and Neurotology / Japan Otological Society (EAONO / JOS) System

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery, 2021
Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj   +1 more source

Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya   +12 more
doaj   +1 more source

Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2023
Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimated that over five million people around the world have suffered from middle ear cholesteatoma.
Dongliang Liu   +3 more
doaj   +1 more source

Value of Endoscopy in Cholesteatoma Clearance: A Systematic Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: The primary goal of cholesteatoma surgery is to eradicate it from the middle ear cleft. However, due to linear axis of illumination of the microscope, in some of the recesses or hidden areas in middle ear are not visualised.
Prakash S Handi   +1 more
doaj   +1 more source

MiR-508-3p promotes proliferation and inhibits apoptosis of middle ear cholesteatoma cells by targeting PTEN/PI3K/AKT pathway

open access: yesInternational Journal of Medical Sciences, 2021
Cholesteatoma of the middle ear is a common disease in otolaryngology, which can lead to serious intracranial and extracranial complications. Recent studies showed that the dysregulation of microRNA may be involved in the formation of middle ear ...
Dongliang Liu, Xiulan Ma
semanticscholar   +1 more source

Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients

open access: yesPLoS ONE, 2020
The middle ear is a small and hard to reach compartment, limiting the amount of tissue that can be extracted and the possibilities for studying the molecular mechanisms behind diseases like cholesteatoma.
Cecilia Drakskog   +6 more
doaj   +2 more sources

The significance of the expression of cell proliferation and inflammation markers in the development of acquired middle ear cholesteatoma [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. Permanent proliferation and periodical infection are the main clinical characteristics of acquired middle ear cholesteatoma. The aim of this study was to research immunohistochemical characteristics of the skin along with the ...
Erdoglija Milan   +5 more
doaj   +1 more source

Transcanal Endoscopic Ear Surgery for Congenital Cholesteatoma [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2018
Objectives As endoscopic instrumentation, techniques and knowledges have significantly improved recently, endoscopic ear surgery has become increasingly popular. Transcanal endoscopic ear surgery (TEES) can provide better visualization of hidden areas in
Joo Hyun Park, Jungmin Ahn, Il Joon Moon
doaj   +1 more source

Animal Models of Middle Ear Cholesteatoma [PDF]

open access: yesBioMed Research International, 2011
Middle ear acquired cholesteatoma is a pathological condition associated with otitis media, which may be associated with temporal bone resorption, otorrhea and hearing loss, and occasionally various other complications. Cholesteatoma is characterized by the enhanced proliferation of epithelial cells with aberrant morphologic characteristics ...
Haruo Takahashi   +2 more
openaire   +3 more sources

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