Results 21 to 30 of about 7,140 (180)

Endoscopic Management of Pediatric Cholesteatoma

Journal of Otology, 2020
Pediatric cholesteatoma occurs in one of two forms: congenital cholesteatoma, developing from embryonic epidermal cell rests or acquired cholesteatoma, associated with a focal defect in the tympanic membrane.
Peter J. Ryan, Nirmal P. Patel
doaj   +1 more source

Non‐coding RNA and cholesteatoma

Laryngoscope Investigative Otolaryngology, 2022
Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master ...
Ivan Jovanovic, Maja Zivkovic, Snezana Jesic, Aleksandra Stankovic   +3 more
doaj   +1 more source

HMGB1 Carried by Small Extracellular Vesicles Potentially Plays a Role in Promoting Acquired Middle Ear Cholesteatoma

Diagnostics, 2023
Cholesteatoma is a specific medical condition involving the abnormal, non-cancerous growth of skin-like tissue in the middle ear, potentially leading to a collection of debris and even infections. The receptor for advanced glycation (RAGE) and its ligand,
Michał W. Łuczak, Karolina Dżaman, Łukasz Zaręba, Katarzyna Czerwaty, Jacek Siewiera, Alicja Głuszko, Ewa Olszewska, Jacek Brzost, Ireneusz Kantor, Mirosław J. Szczepański, Nils Ludwig   +10 more
doaj   +1 more source

Tubotympanic cholesteatoma

Malaysian Family Physician, 2021
Chronic suppurative otitis media is defined as a chronic inflammation of the mucoperiosteal lining of the middle ear cleft. It is described as a persistent disease that is insidious in onset, often capable of causing severe destruction with irreversible sequelae, and clinically present with hearing loss and discharge.
Darshini Nagarajah, Mohd Khairi Md Daud, Nur Syazwani Mohd Salehuddin, Nik Adilah Nik Othman   +3 more
openaire   +3 more sources

Cholesteatoma of the Ear [PDF]

The American Journal of the Medical Sciences, 1894
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openaire   +1 more source

Expression of CYLD and NF-κB in Human Cholesteatoma Epithelium

Mediators of Inflammation, 2010
The tumor suppressor CYLD is a deubiquitinating enzyme that inhibits activation of the NF-κB, which has key roles in inflammation and apoptosis. We hypothesized that CYLD may regulate the NF-κB signaling pathway in cholesteatoma.
Jae Yong Byun, Tae Young Yune, Jee Youn Lee, Seung Geun Yeo, Moon Suh Park   +4 more
doaj   +1 more source

Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Facilitates Cell Proliferation in Human Cholesteatoma Keratinocytes

PPAR Research, 2020
Cholesteatoma is characterized by both the overgrowth of hyperkeratinized squamous epithelium and bone erosion. However, the exact mechanism underlying the hyperproliferative ability of cholesteatoma remains unknown. In this study, we investigated PPAR β/
Chen Zhang, Yang-Wenyi Liu, Zhangcai Chi, Bing Chen   +3 more
doaj   +1 more source

Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma

Laryngoscope Investigative Otolaryngology, 2022
Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya, Ryoukichi Ikeda, Jun Suzuki, Hidetoshi Oshima, Yuri Nomura, Yusuke Kusano, Nobuo Ohta, Tetsuaki Kawase, Kazue Ise, Kazuhiro Murakami, Yasuhiro Nakamura, Hironobu Sasano, Yukio Katori   +12 more
doaj   +1 more source

Pathogenesis and Bone Resorption in Acquired Cholesteatoma: Current Knowledge and Future Prospectives [PDF]

Clinical and Experimental Otorhinolaryngology, 2016
Cholesteatoma is a cystic non tumorous lesion of the temporal bone that has the ability to destroy nearby structures by its power to cause bone resorption and as a result, fatal complications prevail.
Mahmood A. Hamed, Seiichi Nakata, Ramadan H. Sayed, Hiromi Ueda, Badawy S. Badawy, Yoichi Nishimura, Takuro Kojima, Noboru Iwata, Ahmed R. Ahmed, Khalid Dahy, Naoki Kondo, Kenji Suzuki   +11 more
doaj   +1 more source

Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann, Roman Ackermann, Klaus Jahn, John‐Martin Hempel   +3 more
wiley   +1 more source