Results 21 to 30 of about 7,545 (182)

Expression of CYLD and NF-κB in Human Cholesteatoma Epithelium

open access: yesMediators of Inflammation, 2010
The tumor suppressor CYLD is a deubiquitinating enzyme that inhibits activation of the NF-κB, which has key roles in inflammation and apoptosis. We hypothesized that CYLD may regulate the NF-κB signaling pathway in cholesteatoma.
Jae Yong Byun   +4 more
doaj   +1 more source

A Role for Mast Cell-Mediated Antibodies in the Formation of Cholesteatoma and Cholesteatoma-Induced Bone Erosion

open access: yesDiagnostics, 2023
The study aimed to evaluate the effects and relationships between mast cells in the matrix, mast cell enzymes tryptase and chymase, epithelial proliferation, microvascular density, and bone destruction in cholesteatoma.
Çiğdem Özdemir   +7 more
doaj   +1 more source

Cholesteatoma of the Ear [PDF]

open access: yesThe American Journal of the Medical Sciences, 1894
n ...
openaire   +1 more source

Extraintestinal Manifestation of Crohn's Disease in the Middle Ear—A Case Report

open access: yesThe Laryngoscope, EarlyView.
A unique clinical case with extraintestinal manifestation of Crohn's disease in the middle ear, causing severe inflammation and troublesome symptoms. The combination of systemic therapy and surgery curbed the middle ear manifestation upon diagnosis.
Julia Arebro
wiley   +1 more source

Use of Endoscopic Ear Surgery as Adjunct to Microscopic Surgery in Cholesteatoma Surgery

open access: yesB-ENT
This study was conducted to review the value of endoscopic ear surgery as adjunct to microscopic surgery in management of cholesteatoma. It aimed to determine the accessibility of hidden sites and to assess surgical outcomes in cholesteatoma surgery with
Camille Levie, Patrick Levie
doaj   +1 more source

Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya   +12 more
doaj   +1 more source

EHR‐Integrated Synoptic Operative Reporting for Head and Neck Oncologic Surgery

open access: yesThe Laryngoscope, EarlyView.
EHR‐integrated synoptic operative templates for head and neck oncologic surgery was developed and implemented at a tertiary academic cancer center. Departmental adherence rose from 49% to nearly 80% over 6 months, and 94.5% of reviewed cases met targets for complete, internally consistent documentation. The resulting structured data dictionary provides
Miriam N. Lango   +14 more
wiley   +1 more source

Optical Coherence Tomography for Quantitative Point‐of‐Care Ear Imaging

open access: yesThe Laryngoscope, EarlyView.
We evaluated point‐of‐care optical coherence tomography (OCT) otoscopy for quantitative assessment of tympanic membrane (TM) and middle ear pathology in 55 subjects (63 ears), including normal controls, retraction pockets, postoperative ears, perforations, and cholesteatomas.
Marcela A. Morán   +5 more
wiley   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery
Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in ...
Qi Tang   +12 more
doaj   +1 more source

Analysis of KRT1, KRT10, KRT19, TP53 and MMP9 expression in pediatric and adult cholesteatoma.

open access: yesPLoS ONE, 2018
Cholesteatoma is an epidermal cyst with still unknown pathomechanism. The aim of the current study was to investigate molecular differences in the background of the hyperproliferative property and aggressive behavior typical of the cholesteatoma ...
Enikő Palkó   +3 more
doaj   +1 more source

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