Results 41 to 50 of about 11,360 (219)

Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma

Laryngoscope Investigative Otolaryngology, 2022
Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya, Ryoukichi Ikeda, Jun Suzuki, Hidetoshi Oshima, Yuri Nomura, Yusuke Kusano, Nobuo Ohta, Tetsuaki Kawase, Kazue Ise, Kazuhiro Murakami, Yasuhiro Nakamura, Hironobu Sasano, Yukio Katori   +12 more
doaj   +1 more source

A case of cholesteatoma associated with traumatic ear canal stenosis discovered 50 years after injury

Otolaryngology Case Reports, 2021
Acquired ear canal stenosis can be caused by trauma, inflammation, postoperative scar formation, or tumors. There is a risk of cholesteatoma formation because of keratinized deposits in the closed space, with a reduction in quality of life because of ...
Ryota Tomioka, Taro Inagaki, Yoko Ohta, Chiba Yujin, Kiyoaki Tsukahara   +4 more
doaj   +1 more source

Comparison of Computed Tomography-Based Artificial Intelligence Modeling and Magnetic Resonance Imaging in Diagnosis of Cholesteatoma

, 2023
BACKGROUND: In this study, we aimed to compare the success rates of computed tomography image-based artificial intelligence models and magnetic resonance imaging in the diagnosis of preoperative cholesteatoma.
Hanefi Yildirim, Eroğlu, Yeşim, Kaygusuz, İrfan, Hanefi Yıldırım, Cinar, Ahmet, Irfan Kaygusuz, Çınar, Ahmet, Muhammed Yıldırım, Turgut Karlidag, Yıldırım, Hanefi, Erol Keles, Abdulvahap Akyigit, Muhammed Yildirim, Akyiğit, Abdulvahap, Ahmet Cinar, Yalçın, Şinasi, Ahmet Çınar, Karlıdag, Turgut, Orkun Eroglu, Karlidag, Turgut, Yesim Eroglu, Şinasi Yalçın, Turgut Karlıdag, null null, Yalcin, Sinasi, Yıldırım, Muhammed, Eroğlu, Orkun, Yildirim, Muhammed, Keleş, Erol, Sinasi Yalcin   +29 more
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Chronic Draining Ear and Cholesteatoma Recidivism: A Retrospection from Clinical, Imaging, and Surgical Perspectives [PDF]

, 2019
Objective:To evaluate the reasons for persistent draining ear and cholesteatoma recidivism following canal wall down (CWD) tympanomastoidectomy by studying the sensitivity of high-resolution computed tomography (HRCT) scanning in different potential ...
Saumik Das, Tanaya Panja, Mainak Dutta, Ramanuj Sinha   +3 more
core   +1 more source

Modified classification of infralabyrinthie cholesteatoma and scale of cholesteatoma extention [PDF]

, 2020
Introduction. Petrous temporal bone (PTB) cholesteatoma is an epidermal cyst, which is the result of uncontrolled growth of keratinizing squamous epithelium in the petrous part of the temporal bone.
O. S. Panina, O. A. Pashchinina, K. M. Diab   +2 more
core   +1 more source

Cholesteatoma of the Ear [PDF]

The American Journal of the Medical Sciences, 1894
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openaire   +1 more source

Pathology and treatment of cholesteatoma

, 2021
Cholesteatoma is a cystic non-neoplastic lesion of a temporal bone that shows hyperproliferation of keratinocytes and abnormally heavy production of keratin in the tympanic cavity with the influence of chronic inflammation.
Cho, Young Jae
core  

Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Facilitates Cell Proliferation in Human Cholesteatoma Keratinocytes

PPAR Research, 2020
Cholesteatoma is characterized by both the overgrowth of hyperkeratinized squamous epithelium and bone erosion. However, the exact mechanism underlying the hyperproliferative ability of cholesteatoma remains unknown. In this study, we investigated PPAR β/
Chen Zhang, Yang-Wenyi Liu, Zhangcai Chi, Bing Chen   +3 more
doaj   +1 more source

Expression of CYLD and NF-κB in Human Cholesteatoma Epithelium

Mediators of Inflammation, 2010
The tumor suppressor CYLD is a deubiquitinating enzyme that inhibits activation of the NF-κB, which has key roles in inflammation and apoptosis. We hypothesized that CYLD may regulate the NF-κB signaling pathway in cholesteatoma.
Jae Yong Byun, Tae Young Yune, Jee Youn Lee, Seung Geun Yeo, Moon Suh Park   +4 more
doaj   +1 more source

Notch Signaling in Acquired Middle Ear Cholesteatoma [PDF]

, 2021
Hypothesis: We hypothesized that an anomalous change of Notch signaling might be involved in the pathophysiology of cholesteatoma. Background: The Notch signaling pathway regulates integrated growth and differentiation control of keratinocytes.
Fukuda, Atsushi, Hoshino, Kimiko, Shinya Morita, Akihiro Homma, Yuji Nakamaru, Kimiko Hoshino, Morita, Shinya, Atsushi Fukuda, Fujiwara, Keishi, Keishi Fujiwara, Satoshi Kano, Kano, Satoshi, Nakamaru, Yuji, Homma, Akihiro   +13 more
core   +1 more source