Results 201 to 210 of about 1,540,114 (361)

Mechanistic Basis of Cholesterol Binding and Transfer in NPC2: Insights From Molecular Dynamics Simulations. [PDF]

Chembiochem
Patel S, Elghobashi-Meinhardt N.
europepmc   +1 more source

AdipoRon Attenuates Wnt Signaling by Reducing Cholesterol-Dependent Plasma Membrane Rigidity [PDF]

, 2019
Michael L. Salinas, Natividad R. Fuentes, Rachel Choate, Rachel Wright, David N. McMurray, Robert S. Chapkin   +5 more
openalex   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

Targeting cholesterol-driven immunometabolism in cancer: from molecular circuits to clinical translation. [PDF]

Mol Cancer
Ma Q, Chen B, Li T, Lu Y, Li X.
europepmc   +1 more source

Cholesterol granuloma

Pathologica
Campora, Michela, Negri, Giampiero, Longari, Virgilio, Ponzoni, Maurilio   +3 more
openaire   +2 more sources

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Glandular Cells of Forest Musk Deer Autonomously Synthesize Sex Steroid Hormones. [PDF]

Biology (Basel)
An X, Han X, Huang J, Zhang Z, Lou Z, Hu J, Tan R, Yang P, Dou X, Bati H, Zhao Y, Zhang Y, Dou X, Zhang H, Liu S, Yao C.   +15 more
europepmc   +1 more source

The relationship of small dense LDL cholesterol and various parameters of metabolic syndrome in Korean population

, 2015
조용근
openalex   +1 more source

Community Survey on Blood Pressure and Levels of Blood Glucose, Cholesterol and Uric Acid Among People 45 Years and Above in Rural Villages of Bali

, 2022
Putu Sutisna, I Ketut Tangking Widarsa, I Wayan Darwata, I Nengah Kapti   +3 more
openalex   +2 more sources

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source