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Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study.
Annals of Internal Medicine, 2020Risk of coronary heart disease over 14 years was examined prospectively in 2,282 men and 2,845 women according to their antecedent cholesterol and lipoprotein status.
W. Kannel+3 more
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A receptor-mediated pathway for cholesterol homeostasis.
Science, 1986In 1901 a physician, Archibald Garrod, observed a patient with black urine. He used this simple observation to demonstrate that a single mutant gene can produce a discrete block in a biochemical pathway, which he called an “inborn error of metabolism ...
M. Brown, J. Goldstein
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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology.
Science, 1988Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein receptors and, through its interaction with these receptors, participates in the transport of cholesterol and other lipids among various cells of the body.
R. Mahley
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Journal of the American Medical Association (JAMA), 1998
CONTEXT Although cholesterol-reducing treatment has been shown to reduce fatal and nonfatal coronary disease in patients with coronary heart disease (CHD), it is unknown whether benefit from the reduction of low-density lipoprotein cholesterol (LDL-C) in
J. Downs+9 more
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CONTEXT Although cholesterol-reducing treatment has been shown to reduce fatal and nonfatal coronary disease in patients with coronary heart disease (CHD), it is unknown whether benefit from the reduction of low-density lipoprotein cholesterol (LDL-C) in
J. Downs+9 more
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Journal of the American Medical Association (JAMA), 1993
THE SECOND report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II, or ATP II) presents the National Cholesterol Education Program's updated recommendations for cholesterol ...
S. Grundy+27 more
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THE SECOND report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II, or ATP II) presents the National Cholesterol Education Program's updated recommendations for cholesterol ...
S. Grundy+27 more
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Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study.
Journal of the American Medical Association (JAMA), 1986The first report from the Framingham Study that demonstrated an inverse relationship between high-density lipoprotein cholesterol (HDL-C) and the incidence of coronary heart disease (CHD) was based on four years of surveillance.
W. Castelli+5 more
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, 2002
The following abstracts of articles from leading journals and from the ABOG recertification examination have been selected on the basis of their importance to the practice of obstetrics and gynecology.
P. Aul+9 more
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The following abstracts of articles from leading journals and from the ABOG recertification examination have been selected on the basis of their importance to the practice of obstetrics and gynecology.
P. Aul+9 more
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Mechanisms and regulation of cholesterol homeostasis
Nature reviews. Molecular cell biology, 2019Jie Luo, Hongyuan Yang, B. Song
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