Results 11 to 20 of about 33,787 (250)

Expression and purification of human cholesterol 7 alpha-hydroxylase in Escherichia coli.

Journal of Lipid Research, 1994
Cholesterol 7 alpha-hydroxylase (P450c7) is the first and rate-limiting enzyme in bile acid biosynthesis and is the product of a cytochrome P450 gene, CYP7.
W G Karam, J Y Chiang
doaj   +3 more sources

Hormonal regulation of the cholesterol 7 alpha-hydroxylase gene (CYP7)

Journal of Lipid Research, 1995
The transcriptional regulation of the rat cholesterol 7 alpha-hydroxylase gene (CYP7) by hormones and signal transduction pathways was studied by transient transfection assay of the promoter activity. HepG2 cells were transfected with deletion mutants of
M Crestani, D Stroup, J Y Chiang
doaj   +4 more sources

Endotoxin, TNF, and IL-1 decrease cholesterol 7 alpha-hydroxylase mRNA levels and activity.

Journal of Lipid Research, 1996
Endotoxin (LPS) and cytokines increase cholesterol synthesis and the secretion of lipoproteins by the liver in rodents resulting in hypercholesterolemia.
K. Feingold, D. Spady, A. Pollock, A. Moser, C. Grunfeld   +4 more
semanticscholar   +4 more sources

Bile acid excretion and cholesterol 7 alpha-hydroxylase expression in hypercholesterolemia-resistant rabbits

Journal of Lipid Research, 1993
We have developed a partially inbred substrain of New Zealand white rabbits (CRT/mlo) that are resistant to the hypercholesterolemia that accompanies cholesterol feeding to normal rabbits.
JA Poorman, RA Buck, SA Smith, ML Overturf, DS Loose-Mitchell   +4 more
doaj   +3 more sources

Measurement of cholesterol 7 alpha-hydroxylase activity with selected ion monitoring.

Journal of Lipid Research, 1981
Formation of 7 alpha-hydroxycholesterol by rat liver microsomes was quantitated using a gas chromatograph-mass spectrometer operated in selected ion monitoring mode.
A Sanghvi, E Grassi, C Bartman, R Lester, M Galli Kienle, G Galli   +5 more
doaj   +3 more sources

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

Journal of Lipid Research, 1993
Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland, J Drisko, L Graf, D Machleder, AJ Lusis, RA Davis   +5 more
doaj   +3 more sources

Cholesterol 7 alpha-hydroxylase from human liver: partial purification and reconstruction into defined phospholipid-cholesterol vesicles.

Journal of Lipid Research, 1981
Cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme for bile acid synthesis, was shown to be copurified with human liver microsomal cytochrome P-450.
S K Erickson, B Bösterling
doaj   +3 more sources

Dietary fats modulate the regulatory potential of dietary cholesterol on cholesterol 7 alpha-hydroxylase gene expression

Journal of Lipid Research, 1997
Cholesterol 7 alpha-hydroxylase (cyp7) is the rate-limiting enzyme in bile acid biosynthesis. Previously, dietary cholesterol was shown to induce cyp7 gene expression. However, recent studies have produced data that are inconsistent with this observation,
S K Cheema, D Cikaluk, L B Agellon
doaj   +3 more sources

Diets containing sea cucumber (Isostichopus badionotus) meals are hypocholesterolemic in young rats [PDF]

, 2013
Peer reviewedPublisher ...
A Venkateswaran, Alberto Davalos, AO Odegaard, AS Greenberg, AV Khera, BA Janowski, C Zetina Moguel, CD Mathers, DE Kleiner, DJ Gordon, DP Mertz, ER Mojica, FR Van der Leij, G Grant, George Grant, GJ Miller, H Komano, H Leontowicz, HA Tyroler, HH Liu, Hirian Alonso Moshe Barrera-Perez, I Hawa, J Ayo, J Folch, J Lin, J Wen, JC Cohen, JC Cohen, JC Yoon, JD Horton, Jean-Marc A Lobaccaro, JJ Repa, Jorge Montero, Jorge Rubio-Piña, JR Schultz, JW Heinecke, JY Chiang, K Liu, KJ Livak, L Olivera, Leticia Olivera-Castillo, M Yahyavi, MC Damiani, MD Säemann, ME Rodríguez, MF Lopes-Virella, Miguel Angel Olvera-Novoa, N Hasegawa, N Torres, NE Miller, Nina Valadez-Gonzalez, P Araujo, P Lefebvre, Pablo Acereto-Escoffie, RG Herrmann, RK Semple, Roche Diagnostics, Rossanna Rodriguez-Canul, RR Sokal, S Acton, S Najwa, T Park, T Rajamohan, T Sugawara, VL Roger, Víctor Ceja-Moreno, X Duan, X Hu, XQ Hu, XQ Hu, Y Zhong, Yasser Chim-Chi, Z Hossain   +72 more
core   +12 more sources

Oxysterol 7α-Hydroxylase Activity by Cholesterol 7α-Hydroxylase (CYP7A) [PDF]

Journal of Biological Chemistry, 2000
A 7 alpha-hydroxylation is necessary for conversion of both cholesterol and 27-hydroxycholesterol into bile acids. According to current theories, cholesterol 7 alpha-hydroxylase (CYP7A) is responsible for the former and oxysterol 7 alpha-hydroxylase (CYP7B) for the latter reaction.
M, Norlin, U, Andersson, I, Björkhem, K, Wikvall   +3 more
openaire   +2 more sources