Results 191 to 200 of about 33,787 (250)

Investigating the role of genetic variations of <i>ABCB1</i> (rs1045642) and <i>CYP7A1</i> (rs3808607) genes on serum lipid level among Malaysian male patients treated with atorvastatin. [PDF]

Saudi Med J
Afzal MU, Adeeb NB, Musa NF, Noor DA, Athirah Binti Daud NA.   +4 more
europepmc   +1 more source

Oxysterol signaling in the central nervous system: cellular mechanisms and implications for neurodegeneration. [PDF]

Front Mol Neurosci
Ricci RP, Foo CX, Ronacher K, Cullen CL.
europepmc   +1 more source

Regulatory roles of bioactive lipids in vascular homeostasis and remodeling. [PDF]

Med Rev (2021)
Yang J, Xiao H, Zhang Z, Zhang L, Zhang X.   +4 more
europepmc   +1 more source

Development of semi-dwarf Echinacea purpurea by inducing silencing of the endogenous brassinosteroid-biosynthetic gene DWF4. [PDF]

BMC Plant Biol
Zhao J, Liu J, He Y, Fu Y.
europepmc   +1 more source

Targeting HIF-2α in colorectal cancer reveals a cholesterol biosynthesis-dependent ferroptotic vulnerability. [PDF]

Cancer Metab
Dalal PJ, Singhal R, Hu B, Stark D, Rossiter NJ, Jain C, Sajjakulnukit P, Lyssiotis CA, Shah YM.   +8 more
europepmc   +1 more source

Deletion of CH25H and LIPA Genes in Human Abolishes Biosynthesis of 25-Hydroxycholesterol but not of 7α,25-Dihydroxysterols and Enhances Non-enzymatic Cholesterol Oxidation: Metabolic Changes are Partially Reversed by Hematopoietic Stem Cell Transplant^‡

Yutuc E, Ghosh A, Abdel-Khalik J, Goenka A, Asgari MA, Lopez-Castejon G, Beaman GM, Wynn RF, Newman WG, Jones SA, Griffiths WJ, Wang Y.   +11 more
europepmc   +1 more source

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Cholesterol 7- alpha hydroxylase gene ( CYP7A1 ) promoter polymorphism rs3808607 as a risk factor for pulmonary tuberculosis in Egypt

Meta Gene, 2018
Background A major tuberculosis susceptibility locus has been identified by genome wide association study on chromosomal region 8q12-q13. The CYP7A1 gene coding for cholesterol 7a-hydroxylase enzyme is located in this locus, this enzyme is involved in ...
Nevein M. Al-sheikh, Sally M. El-Hefnway, Ahlam A. El-Shetahy   +2 more
semanticscholar   +1 more source

Structure of the rat gene encoding cholesterol 7.alpha.-hydroxylase

Biochemistry, 1990
Cholesterol 7 alpha-hydroxylase (7 alpha-hydroxylase) is a microsomal cytochrome P-450 that catalyzes the first and rate-limiting step in bile acid biosynthesis, the major catabolic pathway in cholesterol homeostasis. The gene encoding the rat 7 alpha-hydroxylase has been isolated and characterized.
D F, Jelinek, D W, Russell
openaire   +2 more sources