Results 51 to 60 of about 33,787 (250)

Cholesterol and 27-hydroxycholesterol 7 alpha-hydroxylation: evidence for two different enzymes.

Journal of Lipid Research, 1993
The use of 2-hydroxypropyl-beta-cyclodextrin as a vehicle for solubilizing cholesterol and 27-hydroxycholesterol has led to a study of their rates of 7 alpha-hydroxylation in microsomal preparations from hamster liver and HepG2 cells.
KO Martin, K Budai, NB Javitt
doaj   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Groen, A.K., Hageman, J., Herrema, H.J., Kuipers, F.   +3 more
core   +3 more sources

Immunochemical Determination of Human Cholesterol 7alpha-Hydroxylase [PDF]

European Journal of Biochemistry, 1995
To produce antibodies for determination of the protein mass of human cholesterol 7 alpha-hydroxylase, a fusion protein was prepared from an in-frame fusion gene containing the cDNA for human cholesterol 7 alpha-hydroxylase near the 3' terminus of the lacZ gene of Escherichia coli.
Y R, Maeda, G, Eggertsen, B, Nyberg, T, Setoguchi, K I, Okuda, K, Einarsson, I, Björkhem   +6 more
openaire   +2 more sources

Esterified and total 7 alpha-hydroxycholesterol in human serum as an indicator for hepatic bile acid synthesis.

Journal of Lipid Research, 1990
Serum levels of 7 alpha-hydroxycholesterol and activities of hepatic microsomal cholesterol 7 alpha-hydroxylase in surgical patients were analyzed by capillary gas-liquid chromatography-selected ion monitoring technique using a new internal standard, 5 ...
H Oda, H Yamashita, K Kosahara, S Kuroki, F Nakayama   +4 more
doaj   +1 more source

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]

, 2017
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H., Charles, Philip D., Dowle, Adam A., Geoghegan, Vincent, Hester, Svenja, Larson, Tony, Rainey, Stephanie M., Sinkins, Steven P., Stainton, Kirsty, Thomas, Benjamin   +9 more
core   +3 more sources

The expression of a catalytically active cholesterol 7 alpha-hydroxylase cytochrome P450 in Escherichia coli.

Journal of Biological Chemistry, 1991
We have recently cloned a full-length cDNA encoding the rat hepatic cholesterol 7 alpha-hydroxylase cytochrome P450 (P450c7) (Li, Y. C., Wang, D. P., and Chiang, J. Y. L. (1990) J. Biol. Chem. 265, 12012-12019), which catalyzes the rate-limiting reaction
Y. Li, J. Chiang
semanticscholar   +1 more source

Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7 alpha-hydroxylase activity and inhibition of bile acid synthesis.

Journal of Lipid Research, 1990
In the chronic bile fistula rat, the administration of a bolus dose of mevinolinic acid, an inhibitor of HMG-CoA reductase, was followed by rapid down-regulation of cholesterol 7 alpha-hydroxylase activity and a decrease in bile acid synthesis.
WM Pandak, ZR Vlahcevic, DM Heuman, PB Hylemon   +3 more
doaj   +1 more source

Study of Changes in Cholesterol 7 Alpha Hydroxylase in Patients with Gall Stone in Babylon Province

, 2018
على الرغم من أن حالة الصراع العسكري والحروب المدمرة كانت هي السمة الغالبة على العلاقات بين الدولتين (الساسانية والبيزنطية), غير أن هذه العلاقات تخللتها أوقات من السلم بسبب عقد معاهدات صلح بين الطرفين إختلفت في شروطها ونتائجها بإختلاف ميزان القوى, وتضمنت ...
Samah Sajad Kadim, M. Al-Mohammadi, A. K. Shaaeli   +2 more
semanticscholar   +1 more source

Molecular targets of hypolipidemic action of sesquiterpene lactones [PDF]

, 2018
Experiments on rats with hyperlipidemia model induced by cholesterol-rich diet during 4 weeks showed that the daily treatment with sesquiterpene lactone grossgemin and ludartin in doses 10 mg/kg for a period of 14 days led to decrease ...
Кайдаш, О. А., Пфаргер, Ю. А.   +1 more
core  

Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. [PDF]

, 2015
Background & aimsAll-trans Retinoic acid (RA) regulates hepatic lipid and bile acid homeostasis. Similar to bile acid (BA), RA accelerates partial hepatectomy (PHx)-induced liver regeneration.
Hu, Ying, Liu, Hui-Xin, Wan, Yu-Jui Yvonne   +2 more
core   +2 more sources