Results 121 to 130 of about 111,376 (287)

Intestinal absorption, hepatic synthesis, and biliary secretion of cholesterol: Where are we for cholesterol gallstone formation? [PDF]

, 2012
Piero Portincasa, David Q.‐H. Wang
openalex   +1 more source

Hepatocyte BPGM Induces RET Lactylation and Macrophage Reprogramming to Promote Tumorigenesis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang, Lu Shi, Liangliang Lin, Yang Zhang, Miao Zhang, Lili Wu, Yong Xia, Yaqiong Zhang, Peng Han, Likun Zhuang, Liang Shi   +10 more
wiley   +1 more source

USE OF DIOSGENIN, YAMOGENIN, TIGOGENIN AND NEOTIGOGENIN FOR TREATMENT OF HYPERLIPIDEMIA BY INHIBITING CHOLESTEROL ABSORPTION IN GIT

, 2019
M Shahina, Shah Murad, Badar Jahan, Khalid Niaz, Aamna Khokhar, Abdul Ghaffar   +5 more
openalex   +2 more sources

Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping

Advanced Science, EarlyView.
This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu, Jie Xie, Xinlin Guo, Liangting Wang, Zhengheng Yu, Xiaopei Qiu, Heng Li, Kang Wang, Xiaoxing Wang, Mingxuan Song, Junsong Guo, Wei Gu, Sergio Bernardini, Chaoyong Yang, Hong Zhang, Yang Luo   +15 more
wiley   +1 more source

Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption. [PDF]

Sci Adv, 2021
Long T, Liu Y, Qin Y, DeBose-Boyd RA, Li X.   +4 more
europepmc   +1 more source

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis. [PDF]

J Atheroscler Thromb, 2022
Shoji T, Akiyama Y, Fujii H, Harada-Shiba M, Ishibashi Y, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsuki K, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H.   +22 more
europepmc   +1 more source

Programmable Multifunctional Bistable Structures for Energy Transfer and Dissipation

Advanced Science, EarlyView.
Utilizing the energy conversion characteristics of asymmetric bistable beams, this study develops a programmable multifunctional system composed of multiple bistable beams for energy transfer and dissipation. The high energy density enables the system to demonstrate potential in transient scenarios such as target delivery and shock absorption ...
Xin Na, Jincong Zhang, Zhicheng Chen, Venkatarao Selamneni, Haotian Chen, Hadi Heidari, Morteza Amjadi   +6 more
wiley   +1 more source

Markers of cholesterol synthesis to cholesterol absorption across the spectrum of non-dialysis CKD: An observational study. [PDF]

Pharmacol Res Perspect, 2021
Emrich IE, Heine GH, Schulze PC, Rogacev KS, Fliser D, Wagenpfeil S, Böhm M, Lütjohann D, Weingärtner O.   +8 more
europepmc   +1 more source

The Effect of Soybean Sterols on the Absorption of Cholesterol by the Rat [PDF]

, 1954
Ray H. Rosenman, Sanford O. Byers, Meyer Friedman   +2 more
openalex   +1 more source