Results 201 to 210 of about 82,690 (331)

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Traditional Chinese medicine monomers: a new strategy against diabetic kidney disease by regulating cholesterol efflux. [PDF]

Front Nutr
Wu C, Sun J, Shi J, Li Z, An Y, Zhu H, Wang L, Liu P.   +7 more
europepmc   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao, Sinan Ai, Yaoxian Wang, Yuning Liu, Jingwei Zhou, Qingqing Liu, Xu Wang, Danting Li, Xin Li, Lin Wang, Jinyi Hou, Liang Peng, Zhen Wang   +12 more
wiley   +1 more source

The association between cholesterol efflux capacity and apolipoprotein A1: systematic review and meta-analysis. [PDF]

Biochem Med (Zagreb)
Černiauskas L, Mazgelytė E, Karčiauskaitė D.   +2 more
europepmc   +1 more source

Production of cholesterol-enriched nascent high density lipoproteins by human monocyte-derived macrophages is a mechanism that contributes to macrophage cholesterol efflux.

, 1994
Howard S. Kruth, S I Skarlatos, Paulette M. Gaynor, W. Gamble   +3 more
openalex   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Improvements in cholesterol efflux capacity of HDL after bariatric surgery in patients with obesity: a meta-analysis. [PDF]

BMC Surg
Jamialahmadi T, Mirhadi E, Reiner Ž, Ahmad S, Sheeha BB, Raba SO, Almahmeed W, Sahebkar A.   +7 more
europepmc   +1 more source

Relationship between Serum Cholesterol Efflux Capacity and Glucose Intolerance in Japanese-Americans

, 2014
Mitsunobu Kubota, Shuhei Nakanishi, Masatoshi Hirano, Shusaku Maeda, Masayasu Yoneda, Tomokazu Awaya, Kiminori Yamane, Nobuoki Kohno   +7 more
openalex   +2 more sources

6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells [PDF]

, 2018
Xiao Li, Jingting Guo, Ning Liang, Xinwei Jiang, Yuan Song, Shiyi Ou, Yunfeng Hu, Rui Jiao, Weibin Bai   +8 more
openalex   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source