Results 191 to 200 of about 588,707 (355)

Regulations of Citrus Pectin Oligosaccharide on Cholesterol Metabolism: Insights from Integrative Analysis of Gut Microbiota and Metabolites [PDF]

Haijuan Hu, Peipei Zhang, Fengxia Liu, Siyi Pan   +3 more
openalex   +1 more source

Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 6

, 2022
Yuri M. Efremov, Anastasia V. Ermolaeva
openalex   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

Advanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang, Tingting Tong, Pengxi Shi, Xiaofan Chen, Chenhao Wang, Qingyuan Weng, Sihan Chen, Linli Que, Qi Chen, Yuehua Li, Qiang Zhu, Jiantao Li   +11 more
wiley   +1 more source

CHOLESTEROL METABOLISM

Journal of Biological Chemistry, 1953
R. Gordon Gould, C. Bruce Taylor, Joanne S. Hagerman, Irving Warner, Donald J. Campbell   +4 more
openaire   +1 more source

Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction

, 2007
Laura Ahtiainen, Julia Kolikova, Aino Mutka, Kaisu Luiro, Massimiliano Gentile, Elina Ikonen, Leonard Khiroug, Anu Jalanko, Outi Kopra   +8 more
openalex   +2 more sources

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source

STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation. [PDF]

Npj Viruses
Agac A, Ludlow M, Knittler MC, Osterhaus ADME, Rimmelzwaan GF, Meineke R.   +5 more
europepmc   +1 more source

Aging and Cholesterol Metabolism

, 2019
Mark T. Mc Auley
openalex   +2 more sources

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

Role of Oxysterol-Binding Protein Family in Cholesterol Metabolism and Cancer Progression: A Review. [PDF]

Med Sci Monit
Wu Y, Lv X, Yang J, Liu S, Chen Y, Yuan Z, Wang X.   +6 more
europepmc   +1 more source