Results 311 to 320 of about 588,707 (355)

Cholesterol metabolism and embryogenesis

Trends in Genetics, 1998
Although cholesterol has long been known to be an essential component of cell membranes in vertebrate organisms, recent studies have suggested that cholesterol plays a crucial role in specific processes during embryonic development, including the covalent modification of Hedgehog proteins.
R V, Farese, J, Herz
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Genetics and cholesterol metabolism

Current Opinion in Lipidology, 1996
The regulation of cholesterol metabolism by both genetic and environmental factors seems to be very complex. The recent research approach focusing on the genetic control of many key regulatory processes of cholesterol homeostasis has, however, started to elucidate the importance of genetic variation in susceptibility to a number of common clinical ...
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Phytosterols and cholesterol metabolism

Current Opinion in Lipidology, 2004
Phytosterols are plant sterols structurally similar to cholesterol that act in the intestine to lower cholesterol absorption. Because they have very low systemic absorption and are already present in healthy diets, increasing the intake of phytosterols may be a practical way to reduce coronary heart disease with minimum risk.Phytosterols displace ...
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CHOLESTEROL-METABOLIZING CYTOCHROMES P450

Drug Metabolism and Disposition, 2006
By catalyzing the first steps in different pathways of cholesterol degradation, cytochromes P450 (P450s) 7A1, 27A1, 11A1, and 46A1 play key roles in cholesterol homeostasis. CYP7A1 is a microsomal liver-specific enzyme that converts cholesterol to 7alpha-hydroxycholesterol.
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Cholesterol Metabolism

Annual Review of Biochemistry, 1956
S O, BYERS, M, FRIEDMAN, S, ST GEORGE
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Cholesterol biosynthesis and metabolism

Cardiovascular Drugs and Therapy, 1992
Cholesterol plays an essential role in cell membrane synthesis and in cell growth and differentiation. In mammalian cells, cholesterol can be synthesized from acetate precursors or taken up from dietary or exogenous sources. The major catabolic route for disposal of cholesterol involves conversion into excretable bile acids.
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Cholesterol Metabolism in Cholesteatoma and Cholesterol Granuloma

Annals of Otology, Rhinology & Laryngology, 1984
Based on biochemical and morphological studies, the significance of cholesterol in cholesteatoma and cholesterol granuloma is discussed. In cholesteatoma, cholesterol is synthesized through desmosterol and Δ7-cholestenol (lathosterol), possibly in the matrix.
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Metabolomics in cancer research and emerging applications in clinical oncology

Ca-A Cancer Journal for Clinicians, 2021
Daniel R Schmidt, David G Kirsch, Caroline A Lewis   +2 more
exaly  

Targeting cancer metabolism in the era of precision oncology

Nature Reviews Drug Discovery, 2021
Zachary T Schug, Joseph M Salvino, Chi V Dang   +2 more
exaly  

Cholesterol Ester Metabolism

Physiological Reviews, 1965
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