Results 171 to 180 of about 262,864 (261)

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan   +7 more
wiley   +1 more source

StarD5 modulates B cell cholesterol synthesis and IgG1 plasma cell differentiation. [PDF]

open access: yesBiochem Biophys Rep
Tharakan A   +6 more
europepmc   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Expression of the cholesterol transporter SR-B1 in melanoma cells facilitates inflammatory signaling leading to reduced cholesterol synthesis. [PDF]

open access: yesNeoplasia
Eckel O   +8 more
europepmc   +1 more source

From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics

open access: yesAdvanced Science, EarlyView.
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil   +3 more
wiley   +1 more source

Regulation of Cholesterol Synthesis

open access: yesJournal of Japan Oil Chemists' Society, 1981
MURAKAWA, Shigeo, ENDO, Akira
openaire   +2 more sources

High glucose levels promote glycolysis and cholesterol synthesis via ERRα and suppress the autophagy-lysosomal pathway in endometrial cancer. [PDF]

open access: yesCell Death Dis
Mao X   +13 more
europepmc   +1 more source

Beyond PEG: Emerging Polymer Lipid Alternatives for Lipid Nanoparticle (LNP) Formulations

open access: yesAdvanced Science, EarlyView.
This review discusses recent advances in PEG‐alternative LNP designs, including non‐PEG polymers, zwitterionic lipids, and polypeptides. It evaluates how surface‐engineering chemistry influences LNP formation and biological behavior, and highlights current limitations and opportunities of PEG‐alternative LNPs.
Zihnil A. I. Mazrad   +4 more
wiley   +1 more source

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